Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer

Introduction: Presence of residual tumors is not an uncommon event after transurethral resection of bladder tumor, and no studies from Nepal so far has addressed this issue. We conducted this study to determine the rate of residual tumors after first transurethral resection of nonmuscle-invasive bl...

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Autores principales:	Pukar Maskey, Pawan Raj Chalise, Uttam Kumar Sharma, Prem Raj Gyawali, Guna Kumar Shrestha, Bhola Raj Joshi
Formato:	article
Lenguaje:	EN
Publicado:	Society of Surgeons of Nepal 2017
Materias:	Nonmuscle invasive bladder tumor Second TURBT TURBT Surgery RD1-811
Acceso en línea:	https://doaj.org/article/6c13a1084b354378bcb0e4e252ebc567
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spelling	oai:doaj.org-article:6c13a1084b354378bcb0e4e252ebc5672021-12-05T19:16:00ZRole of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer10.3126/jssn.v20i2.243791815-39842392-4772https://doaj.org/article/6c13a1084b354378bcb0e4e252ebc5672017-12-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/24379https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: Presence of residual tumors is not an uncommon event after transurethral resection of bladder tumor, and no studies from Nepal so far has addressed this issue. We conducted this study to determine the rate of residual tumors after first transurethral resection of nonmuscle-invasive bladder cancer, and to determine the factors associated with the presence of residual tumors and upstaging of nonmuscle-invasive bladder cancer. Methods: This was a prospective observational study of 43 patients of bladder cancer who had a diagnosis of nonmuscle-invasive bladder cancer following an initial transurethral resection. Demographic data and data on tumor characteristics were obtained. Patients underwent a second transurethral resection within 2 to 8 weeks. Histopathological findings at first and second resection were compared. Results: There were 20 patients with Ta tumor and 23 patiens with T1 tumor at initial resection. Residual tumor was detected in 18 (41.86%) patients overall, 2 in patients with Ta tumor (10%) and 16 in patients with T1 tumor (69.5%). Tumors with T1 stage, high grade, size more than 3 centimeters and sessile growth pattern were seen to have significant association with the presence of residual tumors. Six patients with T1 disease upstaged to T2 disease after second resection (26%), while there were no upstaging with Ta tumors. Tumors with T1 stage, sessile configuration and size more than 3 centimeters were found to be significantly associated with upstaging. Conclusion: A second transurethral resection for nonmuscle-invasive bladder cancer should be considered if the initial tumor is T1 stage, high grade, more than 3 centimeters in size and has sessile growth pattern. Pukar MaskeyPawan Raj ChaliseUttam Kumar SharmaPrem Raj GyawaliGuna Kumar ShresthaBhola Raj JoshiSociety of Surgeons of NepalarticleNonmuscle invasive bladder tumorSecond TURBTTURBTSurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 20, Iss 2 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Nonmuscle invasive bladder tumor Second TURBT TURBT Surgery RD1-811
spellingShingle	Nonmuscle invasive bladder tumor Second TURBT TURBT Surgery RD1-811 Pukar Maskey Pawan Raj Chalise Uttam Kumar Sharma Prem Raj Gyawali Guna Kumar Shrestha Bhola Raj Joshi Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
description	Introduction: Presence of residual tumors is not an uncommon event after transurethral resection of bladder tumor, and no studies from Nepal so far has addressed this issue. We conducted this study to determine the rate of residual tumors after first transurethral resection of nonmuscle-invasive bladder cancer, and to determine the factors associated with the presence of residual tumors and upstaging of nonmuscle-invasive bladder cancer. Methods: This was a prospective observational study of 43 patients of bladder cancer who had a diagnosis of nonmuscle-invasive bladder cancer following an initial transurethral resection. Demographic data and data on tumor characteristics were obtained. Patients underwent a second transurethral resection within 2 to 8 weeks. Histopathological findings at first and second resection were compared. Results: There were 20 patients with Ta tumor and 23 patiens with T1 tumor at initial resection. Residual tumor was detected in 18 (41.86%) patients overall, 2 in patients with Ta tumor (10%) and 16 in patients with T1 tumor (69.5%). Tumors with T1 stage, high grade, size more than 3 centimeters and sessile growth pattern were seen to have significant association with the presence of residual tumors. Six patients with T1 disease upstaged to T2 disease after second resection (26%), while there were no upstaging with Ta tumors. Tumors with T1 stage, sessile configuration and size more than 3 centimeters were found to be significantly associated with upstaging. Conclusion: A second transurethral resection for nonmuscle-invasive bladder cancer should be considered if the initial tumor is T1 stage, high grade, more than 3 centimeters in size and has sessile growth pattern.
format	article
author	Pukar Maskey Pawan Raj Chalise Uttam Kumar Sharma Prem Raj Gyawali Guna Kumar Shrestha Bhola Raj Joshi
author_facet	Pukar Maskey Pawan Raj Chalise Uttam Kumar Sharma Prem Raj Gyawali Guna Kumar Shrestha Bhola Raj Joshi
author_sort	Pukar Maskey
title	Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
title_short	Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
title_full	Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
title_fullStr	Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
title_full_unstemmed	Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
title_sort	role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer
publisher	Society of Surgeons of Nepal
publishDate	2017
url	https://doaj.org/article/6c13a1084b354378bcb0e4e252ebc567
work_keys_str_mv	AT pukarmaskey roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer AT pawanrajchalise roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer AT uttamkumarsharma roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer AT premrajgyawali roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer AT gunakumarshrestha roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer AT bholarajjoshi roleofsecondtransurethralresectionindeterminingresidualtumorinnonmuscleinvasivebladdercancer
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Role of second transurethral resection in determining residual tumor in nonmuscle-invasive bladder cancer

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