Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion

Ken Ogino, Akitaka Tsujikawa, Tomoaki Murakami, Yuki Muraoka, Yumiko Kurashige, Nagahisa YoshimuraDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanPurpose: To report the efficacy of grid photocoagulation combined with intravitreal bevacizumab...

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Autores principales:	Ogino K, Tsujikawa A, Murakami T, Muraoka Y, Kurashige Y, Yoshimura N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/6c1fb19896e147c8b0a27d3a1dbb1f5e
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spelling	oai:doaj.org-article:6c1fb19896e147c8b0a27d3a1dbb1f5e2021-12-02T01:53:22ZGrid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion1177-54671177-5483https://doaj.org/article/6c1fb19896e147c8b0a27d3a1dbb1f5e2011-07-01T00:00:00Zhttp://www.dovepress.com/grid-photocoagulation-combined-with-intravitreal-bevacizumab-for-recur-a7954https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ken Ogino, Akitaka Tsujikawa, Tomoaki Murakami, Yuki Muraoka, Yumiko Kurashige, Nagahisa YoshimuraDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanPurpose: To report the efficacy of grid photocoagulation combined with intravitreal bevacizumab (IVB) for macular edema recurring after previous IVBs associated with retinal vein occlusion (RVO).Methods: This retrospective study consisted of 19 eyes with branch retinal vein occlusion (BRVO) and nine eyes with central retinal vein occlusion (CRVO), which were treated with grid photocoagulation combined with IVB for recurrent macular edema after previous IVBs. The mean duration of total follow-up was 29.3 &plusmn; 5.8 months.Results: After this combination therapy, foveal thickness was reduced, significant with slight improvement in visual acuity (VA). At 1 month after treatment, although 25 of the 28 eyes showed complete resolution of the cystoid space, the macular edema recurred to some extent in 19 eyes. Compared with initial values, final foveal thickness was reduced significantly in both BRVO and CRVO groups (P &lt; 0.001), but improvement in VA was significant only for eyes with BRVO (P = 0.012). The total number of IVB was 2.8 &plusmn; 0.7 for eyes with either BRVO or CRVO.Conclusion: Grid photocoagulation combined with IVB has a substantial effect on reducing recurrent macular edema associated with RVO, but the effect on visual acuity is limited.Keywords: bevacizumab, grid laser photocoagulation, macular edema, optical coherence tomography, retinal vein occlusionOgino KTsujikawa AMurakami TMuraoka YKurashige YYoshimura NDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1031-1036 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Ogino K Tsujikawa A Murakami T Muraoka Y Kurashige Y Yoshimura N Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
description	Ken Ogino, Akitaka Tsujikawa, Tomoaki Murakami, Yuki Muraoka, Yumiko Kurashige, Nagahisa YoshimuraDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanPurpose: To report the efficacy of grid photocoagulation combined with intravitreal bevacizumab (IVB) for macular edema recurring after previous IVBs associated with retinal vein occlusion (RVO).Methods: This retrospective study consisted of 19 eyes with branch retinal vein occlusion (BRVO) and nine eyes with central retinal vein occlusion (CRVO), which were treated with grid photocoagulation combined with IVB for recurrent macular edema after previous IVBs. The mean duration of total follow-up was 29.3 &plusmn; 5.8 months.Results: After this combination therapy, foveal thickness was reduced, significant with slight improvement in visual acuity (VA). At 1 month after treatment, although 25 of the 28 eyes showed complete resolution of the cystoid space, the macular edema recurred to some extent in 19 eyes. Compared with initial values, final foveal thickness was reduced significantly in both BRVO and CRVO groups (P &lt; 0.001), but improvement in VA was significant only for eyes with BRVO (P = 0.012). The total number of IVB was 2.8 &plusmn; 0.7 for eyes with either BRVO or CRVO.Conclusion: Grid photocoagulation combined with IVB has a substantial effect on reducing recurrent macular edema associated with RVO, but the effect on visual acuity is limited.Keywords: bevacizumab, grid laser photocoagulation, macular edema, optical coherence tomography, retinal vein occlusion
format	article
author	Ogino K Tsujikawa A Murakami T Muraoka Y Kurashige Y Yoshimura N
author_facet	Ogino K Tsujikawa A Murakami T Muraoka Y Kurashige Y Yoshimura N
author_sort	Ogino K
title	Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
title_short	Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
title_full	Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
title_fullStr	Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
title_full_unstemmed	Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
title_sort	grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/6c1fb19896e147c8b0a27d3a1dbb1f5e
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Grid photocoagulation combined with intravitreal bevacizumab for recurrent macular edema associated with retinal vein occlusion

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