Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

Reactive oxygen species in the tumour microenvironment can have an immunosuppressive effect. Here, the authors devise a nanoparticle that anchors to the extracellular matrix within tumours and scavenges reactive oxygen species, resulting in an enhanced immune response within the tumour.

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Autores principales:	Hongzhang Deng, Weijing Yang, Zijian Zhou, Rui Tian, Lisen Lin, Ying Ma, Jibin Song, Xiaoyuan Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c21e9ca5cb844c9b35d0eb97ba614a6
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spelling	oai:doaj.org-article:6c21e9ca5cb844c9b35d0eb97ba614a62021-12-02T17:37:42ZTargeted scavenging of extracellular ROS relieves suppressive immunogenic cell death10.1038/s41467-020-18745-62041-1723https://doaj.org/article/6c21e9ca5cb844c9b35d0eb97ba614a62020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18745-6https://doaj.org/toc/2041-1723Reactive oxygen species in the tumour microenvironment can have an immunosuppressive effect. Here, the authors devise a nanoparticle that anchors to the extracellular matrix within tumours and scavenges reactive oxygen species, resulting in an enhanced immune response within the tumour.Hongzhang DengWeijing YangZijian ZhouRui TianLisen LinYing MaJibin SongXiaoyuan ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hongzhang Deng Weijing Yang Zijian Zhou Rui Tian Lisen Lin Ying Ma Jibin Song Xiaoyuan Chen Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
description	Reactive oxygen species in the tumour microenvironment can have an immunosuppressive effect. Here, the authors devise a nanoparticle that anchors to the extracellular matrix within tumours and scavenges reactive oxygen species, resulting in an enhanced immune response within the tumour.
format	article
author	Hongzhang Deng Weijing Yang Zijian Zhou Rui Tian Lisen Lin Ying Ma Jibin Song Xiaoyuan Chen
author_facet	Hongzhang Deng Weijing Yang Zijian Zhou Rui Tian Lisen Lin Ying Ma Jibin Song Xiaoyuan Chen
author_sort	Hongzhang Deng
title	Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
title_short	Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
title_full	Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
title_fullStr	Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
title_full_unstemmed	Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
title_sort	targeted scavenging of extracellular ros relieves suppressive immunogenic cell death
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6c21e9ca5cb844c9b35d0eb97ba614a6
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Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death

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