NASC-seq monitors RNA synthesis in single cells

Sequencing of newly synthesised RNA can reveal the transcriptional dynamics in a population of cells. Here the authors develop NASC-seq to bring this sensitivity and temporal resolution to single-cell analysis.

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Autores principales:	Gert-Jan Hendriks, Lisa A. Jung, Anton J. M. Larsson, Michael Lidschreiber, Oscar Andersson Forsman, Katja Lidschreiber, Patrick Cramer, Rickard Sandberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c2539c49151440bae8f5d6aea33b041
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id	oai:doaj.org-article:6c2539c49151440bae8f5d6aea33b041
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spelling	oai:doaj.org-article:6c2539c49151440bae8f5d6aea33b0412021-12-02T17:01:45ZNASC-seq monitors RNA synthesis in single cells10.1038/s41467-019-11028-92041-1723https://doaj.org/article/6c2539c49151440bae8f5d6aea33b0412019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11028-9https://doaj.org/toc/2041-1723Sequencing of newly synthesised RNA can reveal the transcriptional dynamics in a population of cells. Here the authors develop NASC-seq to bring this sensitivity and temporal resolution to single-cell analysis.Gert-Jan HendriksLisa A. JungAnton J. M. LarssonMichael LidschreiberOscar Andersson ForsmanKatja LidschreiberPatrick CramerRickard SandbergNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gert-Jan Hendriks Lisa A. Jung Anton J. M. Larsson Michael Lidschreiber Oscar Andersson Forsman Katja Lidschreiber Patrick Cramer Rickard Sandberg NASC-seq monitors RNA synthesis in single cells
description	Sequencing of newly synthesised RNA can reveal the transcriptional dynamics in a population of cells. Here the authors develop NASC-seq to bring this sensitivity and temporal resolution to single-cell analysis.
format	article
author	Gert-Jan Hendriks Lisa A. Jung Anton J. M. Larsson Michael Lidschreiber Oscar Andersson Forsman Katja Lidschreiber Patrick Cramer Rickard Sandberg
author_facet	Gert-Jan Hendriks Lisa A. Jung Anton J. M. Larsson Michael Lidschreiber Oscar Andersson Forsman Katja Lidschreiber Patrick Cramer Rickard Sandberg
author_sort	Gert-Jan Hendriks
title	NASC-seq monitors RNA synthesis in single cells
title_short	NASC-seq monitors RNA synthesis in single cells
title_full	NASC-seq monitors RNA synthesis in single cells
title_fullStr	NASC-seq monitors RNA synthesis in single cells
title_full_unstemmed	NASC-seq monitors RNA synthesis in single cells
title_sort	nasc-seq monitors rna synthesis in single cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6c2539c49151440bae8f5d6aea33b041
work_keys_str_mv	AT gertjanhendriks nascseqmonitorsrnasynthesisinsinglecells AT lisaajung nascseqmonitorsrnasynthesisinsinglecells AT antonjmlarsson nascseqmonitorsrnasynthesisinsinglecells AT michaellidschreiber nascseqmonitorsrnasynthesisinsinglecells AT oscaranderssonforsman nascseqmonitorsrnasynthesisinsinglecells AT katjalidschreiber nascseqmonitorsrnasynthesisinsinglecells AT patrickcramer nascseqmonitorsrnasynthesisinsinglecells AT rickardsandberg nascseqmonitorsrnasynthesisinsinglecells
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NASC-seq monitors RNA synthesis in single cells

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