Semen inhibits Zika virus infection of cells and tissues from the anogenital region
Semen from Zika virus infected individuals can contain high viral loads and can result in sexual transmission. Here, Müller et al. show that semen, and particularly seminal preparations containing extracellular vesicles, inhibit infection of Zika and other flaviviruses.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6c32bac538ea4152bde13f0d2dad20ed |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6c32bac538ea4152bde13f0d2dad20ed |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6c32bac538ea4152bde13f0d2dad20ed2021-12-02T14:41:16ZSemen inhibits Zika virus infection of cells and tissues from the anogenital region10.1038/s41467-018-04442-y2041-1723https://doaj.org/article/6c32bac538ea4152bde13f0d2dad20ed2018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04442-yhttps://doaj.org/toc/2041-1723Semen from Zika virus infected individuals can contain high viral loads and can result in sexual transmission. Here, Müller et al. show that semen, and particularly seminal preparations containing extracellular vesicles, inhibit infection of Zika and other flaviviruses.Janis A. MüllerMirja HarmsFranziska KrügerRüdiger GroßSimone JoasManuel HaynAndrea N. DietzSina LippoldJens von EinemAxel SchubertManuela MichelBenjamin MayerMirko CorteseKaren S. JangNathallie Sandi-MonroyMiriam DenizFlorian EbnerOlli VapalahtiMarkus OttoRalf BartenschlagerJean-Philippe HerbeuvalJonas Schmidt-ChanasitNadia R. RoanJan MünchNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Janis A. Müller Mirja Harms Franziska Krüger Rüdiger Groß Simone Joas Manuel Hayn Andrea N. Dietz Sina Lippold Jens von Einem Axel Schubert Manuela Michel Benjamin Mayer Mirko Cortese Karen S. Jang Nathallie Sandi-Monroy Miriam Deniz Florian Ebner Olli Vapalahti Markus Otto Ralf Bartenschlager Jean-Philippe Herbeuval Jonas Schmidt-Chanasit Nadia R. Roan Jan Münch Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| description |
Semen from Zika virus infected individuals can contain high viral loads and can result in sexual transmission. Here, Müller et al. show that semen, and particularly seminal preparations containing extracellular vesicles, inhibit infection of Zika and other flaviviruses. |
| format |
article |
| author |
Janis A. Müller Mirja Harms Franziska Krüger Rüdiger Groß Simone Joas Manuel Hayn Andrea N. Dietz Sina Lippold Jens von Einem Axel Schubert Manuela Michel Benjamin Mayer Mirko Cortese Karen S. Jang Nathallie Sandi-Monroy Miriam Deniz Florian Ebner Olli Vapalahti Markus Otto Ralf Bartenschlager Jean-Philippe Herbeuval Jonas Schmidt-Chanasit Nadia R. Roan Jan Münch |
| author_facet |
Janis A. Müller Mirja Harms Franziska Krüger Rüdiger Groß Simone Joas Manuel Hayn Andrea N. Dietz Sina Lippold Jens von Einem Axel Schubert Manuela Michel Benjamin Mayer Mirko Cortese Karen S. Jang Nathallie Sandi-Monroy Miriam Deniz Florian Ebner Olli Vapalahti Markus Otto Ralf Bartenschlager Jean-Philippe Herbeuval Jonas Schmidt-Chanasit Nadia R. Roan Jan Münch |
| author_sort |
Janis A. Müller |
| title |
Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| title_short |
Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| title_full |
Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| title_fullStr |
Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| title_full_unstemmed |
Semen inhibits Zika virus infection of cells and tissues from the anogenital region |
| title_sort |
semen inhibits zika virus infection of cells and tissues from the anogenital region |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/6c32bac538ea4152bde13f0d2dad20ed |
| work_keys_str_mv |
AT janisamuller semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT mirjaharms semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT franziskakruger semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT rudigergroß semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT simonejoas semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT manuelhayn semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT andreandietz semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT sinalippold semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT jensvoneinem semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT axelschubert semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT manuelamichel semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT benjaminmayer semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT mirkocortese semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT karensjang semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT nathalliesandimonroy semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT miriamdeniz semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT florianebner semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT ollivapalahti semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT markusotto semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT ralfbartenschlager semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT jeanphilippeherbeuval semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT jonasschmidtchanasit semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT nadiarroan semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion AT janmunch semeninhibitszikavirusinfectionofcellsandtissuesfromtheanogenitalregion |
| _version_ |
1718389934906146816 |