A rice gene of de novo origin negatively regulates pathogen-induced defense response.
How defense genes originated with the evolution of their specific pathogen-responsive traits remains an important problem. It is generally known that a form of duplication can generate new genes, suggesting that a new gene usually evolves from an ancestral gene. However, we show that a new defense g...
Guardado en:
| Autores principales: | , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Public Library of Science (PLoS)
2009
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/6c368c5e2aae4fd38454da84b2a6b8b3 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:6c368c5e2aae4fd38454da84b2a6b8b3 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:6c368c5e2aae4fd38454da84b2a6b8b32021-11-25T06:17:06ZA rice gene of de novo origin negatively regulates pathogen-induced defense response.1932-620310.1371/journal.pone.0004603https://doaj.org/article/6c368c5e2aae4fd38454da84b2a6b8b32009-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19240804/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203How defense genes originated with the evolution of their specific pathogen-responsive traits remains an important problem. It is generally known that a form of duplication can generate new genes, suggesting that a new gene usually evolves from an ancestral gene. However, we show that a new defense gene in plants may evolve by de novo origination, resulting in sophisticated disease-resistant functions in rice. Analyses of gene evolution showed that this new gene, OsDR10, had homologs only in the closest relative, Leersia genus, but not other subfamilies of the grass family; therefore, it is a rice tribe-specific gene that may have originated de novo in the tribe. We further show that this gene may evolve a highly conservative rice-specific function that contributes to the regulation difference between rice and other plant species in response to pathogen infections. Biologic analyses including gene silencing, pathologic analysis, and mutant characterization by transformation showed that the OsDR10-suppressed plants enhanced resistance to a broad spectrum of Xanthomonas oryzae pv. oryzae strains, which cause bacterial blight disease. This enhanced disease resistance was accompanied by increased accumulation of endogenous salicylic acid (SA) and suppressed accumulation of endogenous jasmonic acid (JA) as well as modified expression of a subset of defense-responsive genes functioning both upstream and downstream of SA and JA. These data and analyses provide fresh insights into the new biologic and evolutionary processes of a de novo gene recruited rapidly.Wenfei XiaoHongbo LiuYu LiXianghua LiCaiguo XuManyuan LongShiping WangPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 4, Iss 2, p e4603 (2009) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Wenfei Xiao Hongbo Liu Yu Li Xianghua Li Caiguo Xu Manyuan Long Shiping Wang A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| description |
How defense genes originated with the evolution of their specific pathogen-responsive traits remains an important problem. It is generally known that a form of duplication can generate new genes, suggesting that a new gene usually evolves from an ancestral gene. However, we show that a new defense gene in plants may evolve by de novo origination, resulting in sophisticated disease-resistant functions in rice. Analyses of gene evolution showed that this new gene, OsDR10, had homologs only in the closest relative, Leersia genus, but not other subfamilies of the grass family; therefore, it is a rice tribe-specific gene that may have originated de novo in the tribe. We further show that this gene may evolve a highly conservative rice-specific function that contributes to the regulation difference between rice and other plant species in response to pathogen infections. Biologic analyses including gene silencing, pathologic analysis, and mutant characterization by transformation showed that the OsDR10-suppressed plants enhanced resistance to a broad spectrum of Xanthomonas oryzae pv. oryzae strains, which cause bacterial blight disease. This enhanced disease resistance was accompanied by increased accumulation of endogenous salicylic acid (SA) and suppressed accumulation of endogenous jasmonic acid (JA) as well as modified expression of a subset of defense-responsive genes functioning both upstream and downstream of SA and JA. These data and analyses provide fresh insights into the new biologic and evolutionary processes of a de novo gene recruited rapidly. |
| format |
article |
| author |
Wenfei Xiao Hongbo Liu Yu Li Xianghua Li Caiguo Xu Manyuan Long Shiping Wang |
| author_facet |
Wenfei Xiao Hongbo Liu Yu Li Xianghua Li Caiguo Xu Manyuan Long Shiping Wang |
| author_sort |
Wenfei Xiao |
| title |
A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| title_short |
A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| title_full |
A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| title_fullStr |
A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| title_full_unstemmed |
A rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| title_sort |
rice gene of de novo origin negatively regulates pathogen-induced defense response. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2009 |
| url |
https://doaj.org/article/6c368c5e2aae4fd38454da84b2a6b8b3 |
| work_keys_str_mv |
AT wenfeixiao aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT hongboliu aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT yuli aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT xianghuali aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT caiguoxu aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT manyuanlong aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT shipingwang aricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT wenfeixiao ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT hongboliu ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT yuli ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT xianghuali ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT caiguoxu ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT manyuanlong ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse AT shipingwang ricegeneofdenovooriginnegativelyregulatespathogeninduceddefenseresponse |
| _version_ |
1718413988849516544 |