The role of GPR56/ADGRG1 in health and disease

GPR56/ADGRG1 is a versatile adhesion G protein-coupled receptor important in the physiological functions of the central and peripheral nervous systems, reproductive system, muscle hypertrophy, immune regulation, and hematopoietic stem cell generation. By contrast, aberrant expression or deregulated...

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Autores principales:	Abhishek Kumar Singh, Hsi-Hsien Lin
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Adhesion GPCR G protein Ligand Signaling Medicine (General) R5-920 Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/6c393340044d4d2885bc824001406153
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spelling	oai:doaj.org-article:6c393340044d4d2885bc8240014061532021-11-28T04:33:12ZThe role of GPR56/ADGRG1 in health and disease2319-417010.1016/j.bj.2021.04.012https://doaj.org/article/6c393340044d4d2885bc8240014061532021-10-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2319417021000445https://doaj.org/toc/2319-4170GPR56/ADGRG1 is a versatile adhesion G protein-coupled receptor important in the physiological functions of the central and peripheral nervous systems, reproductive system, muscle hypertrophy, immune regulation, and hematopoietic stem cell generation. By contrast, aberrant expression or deregulated functions of GPR56 have been implicated in diverse pathological processes, including bilateral frontoparietal polymicrogyria, depression, and tumorigenesis. In this review article, we summarize and discuss the current understandings of the role of GPR56 in health and disease.Abhishek Kumar SinghHsi-Hsien LinElsevierarticleAdhesion GPCRG proteinLigandSignalingMedicine (General)R5-920Biology (General)QH301-705.5ENBiomedical Journal, Vol 44, Iss 5, Pp 534-547 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Adhesion GPCR G protein Ligand Signaling Medicine (General) R5-920 Biology (General) QH301-705.5
spellingShingle	Adhesion GPCR G protein Ligand Signaling Medicine (General) R5-920 Biology (General) QH301-705.5 Abhishek Kumar Singh Hsi-Hsien Lin The role of GPR56/ADGRG1 in health and disease
description	GPR56/ADGRG1 is a versatile adhesion G protein-coupled receptor important in the physiological functions of the central and peripheral nervous systems, reproductive system, muscle hypertrophy, immune regulation, and hematopoietic stem cell generation. By contrast, aberrant expression or deregulated functions of GPR56 have been implicated in diverse pathological processes, including bilateral frontoparietal polymicrogyria, depression, and tumorigenesis. In this review article, we summarize and discuss the current understandings of the role of GPR56 in health and disease.
format	article
author	Abhishek Kumar Singh Hsi-Hsien Lin
author_facet	Abhishek Kumar Singh Hsi-Hsien Lin
author_sort	Abhishek Kumar Singh
title	The role of GPR56/ADGRG1 in health and disease
title_short	The role of GPR56/ADGRG1 in health and disease
title_full	The role of GPR56/ADGRG1 in health and disease
title_fullStr	The role of GPR56/ADGRG1 in health and disease
title_full_unstemmed	The role of GPR56/ADGRG1 in health and disease
title_sort	role of gpr56/adgrg1 in health and disease
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/6c393340044d4d2885bc824001406153
work_keys_str_mv	AT abhishekkumarsingh theroleofgpr56adgrg1inhealthanddisease AT hsihsienlin theroleofgpr56adgrg1inhealthanddisease AT abhishekkumarsingh roleofgpr56adgrg1inhealthanddisease AT hsihsienlin roleofgpr56adgrg1inhealthanddisease
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The role of GPR56/ADGRG1 in health and disease

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