Astrocytic GABA transporter activity modulates excitatory neurotransmission

Astrocytic GABA transporter activity modulates excitatory neurotransmission

Astrocytes monitor and regulate both excitatory and inhibitory synaptic activity. Here, the authors identify a novel form of neuronal-glia communication, by which astrocytes detect rises in GABA via the GABA transporter GAT-3; this results in adenosine release that acts presynaptically to inhibit ne...

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Autores principales: Kim Boddum, Thomas P. Jensen, Vincent Magloire, Uffe Kristiansen, Dmitri A. Rusakov, Ivan Pavlov, Matthew C. Walker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
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Acceso en línea:https://doaj.org/article/6c3a64f69f364f18a63aed2e76e83135
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