Common variants upstream of KDR encoding VEGFR2 and in TTC39B associate with endometriosis

Common variants upstream of KDR encoding VEGFR2 and in TTC39B associate with endometriosis

Endometriosis is a common gynaecological disease but the underlying pathogenesis is poorly understood, however there is a strong familial component. Here the authors conduct a genome wide association study and identify a novel susceptibility locus that correlates with disease severity.

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Bibliographic Details
Main Authors: Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Kristrun Aradottir, Bjarke Feenstra, Asgeir Sigurdsson, Lilja Stefansdottir, Anna M. Kristinsdottir, Florian Zink, Gisli H. Halldorsson, Nete Munk Nielsen, Frank Geller, Mads Melbye, Daniel F. Gudbjartsson, Reynir T. Geirsson, Unnur Thorsteinsdottir, Kari Stefansson
Format: article
Language:EN
Published: Nature Portfolio 2016
Subjects:
Science
Q
Online Access:https://doaj.org/article/6c41abb3afba4f8a8463de22de52ead8
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Internet

https://doaj.org/article/6c41abb3afba4f8a8463de22de52ead8

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