Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis

Engineering dynamic control can improve microbial production of target chemicals. Here, the authors design a sensor-regulator and RNAi based bifunctional dynamic control network that can simultaneously and independently turn up and down cellular metabolism for engineered muconic acid production in E...

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Autores principales:	Yaping Yang, Yuheng Lin, Jian Wang, Yifei Wu, Ruihua Zhang, Mengyin Cheng, Xiaolin Shen, Jia Wang, Zhenya Chen, Chenyi Li, Qipeng Yuan, Yajun Yan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c41fd6cf0b14e55acf1811ff0d399e9
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spelling	oai:doaj.org-article:6c41fd6cf0b14e55acf1811ff0d399e92021-12-02T14:39:24ZSensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis10.1038/s41467-018-05466-02041-1723https://doaj.org/article/6c41fd6cf0b14e55acf1811ff0d399e92018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05466-0https://doaj.org/toc/2041-1723Engineering dynamic control can improve microbial production of target chemicals. Here, the authors design a sensor-regulator and RNAi based bifunctional dynamic control network that can simultaneously and independently turn up and down cellular metabolism for engineered muconic acid production in E. coli.Yaping YangYuheng LinJian WangYifei WuRuihua ZhangMengyin ChengXiaolin ShenJia WangZhenya ChenChenyi LiQipeng YuanYajun YanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yaping Yang Yuheng Lin Jian Wang Yifei Wu Ruihua Zhang Mengyin Cheng Xiaolin Shen Jia Wang Zhenya Chen Chenyi Li Qipeng Yuan Yajun Yan Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
description	Engineering dynamic control can improve microbial production of target chemicals. Here, the authors design a sensor-regulator and RNAi based bifunctional dynamic control network that can simultaneously and independently turn up and down cellular metabolism for engineered muconic acid production in E. coli.
format	article
author	Yaping Yang Yuheng Lin Jian Wang Yifei Wu Ruihua Zhang Mengyin Cheng Xiaolin Shen Jia Wang Zhenya Chen Chenyi Li Qipeng Yuan Yajun Yan
author_facet	Yaping Yang Yuheng Lin Jian Wang Yifei Wu Ruihua Zhang Mengyin Cheng Xiaolin Shen Jia Wang Zhenya Chen Chenyi Li Qipeng Yuan Yajun Yan
author_sort	Yaping Yang
title	Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
title_short	Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
title_full	Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
title_fullStr	Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
title_full_unstemmed	Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis
title_sort	sensor-regulator and rnai based bifunctional dynamic control network for engineered microbial synthesis
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6c41fd6cf0b14e55acf1811ff0d399e9
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Sensor-regulator and RNAi based bifunctional dynamic control network for engineered microbial synthesis

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