Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma

Respiratory syncytial virus (RSV) bronchiolitis during infancy is a major risk factor for asthma development. Here, Raita et al. integrate clinical data with airway microbiome, transcriptome, and metabolome data and identity four endotypes with differential risks for developing asthma.

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Autores principales:	Yoshihiko Raita, Marcos Pérez-Losada, Robert J. Freishtat, Brennan Harmon, Jonathan M. Mansbach, Pedro A. Piedra, Zhaozhong Zhu, Carlos A. Camargo, Kohei Hasegawa
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c472cd962914c2c8b3f0373e27d5a0a
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spelling	oai:doaj.org-article:6c472cd962914c2c8b3f0373e27d5a0a2021-12-02T17:40:00ZIntegrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma10.1038/s41467-021-23859-62041-1723https://doaj.org/article/6c472cd962914c2c8b3f0373e27d5a0a2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23859-6https://doaj.org/toc/2041-1723Respiratory syncytial virus (RSV) bronchiolitis during infancy is a major risk factor for asthma development. Here, Raita et al. integrate clinical data with airway microbiome, transcriptome, and metabolome data and identity four endotypes with differential risks for developing asthma.Yoshihiko RaitaMarcos Pérez-LosadaRobert J. FreishtatBrennan HarmonJonathan M. MansbachPedro A. PiedraZhaozhong ZhuCarlos A. CamargoKohei HasegawaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yoshihiko Raita Marcos Pérez-Losada Robert J. Freishtat Brennan Harmon Jonathan M. Mansbach Pedro A. Piedra Zhaozhong Zhu Carlos A. Camargo Kohei Hasegawa Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
description	Respiratory syncytial virus (RSV) bronchiolitis during infancy is a major risk factor for asthma development. Here, Raita et al. integrate clinical data with airway microbiome, transcriptome, and metabolome data and identity four endotypes with differential risks for developing asthma.
format	article
author	Yoshihiko Raita Marcos Pérez-Losada Robert J. Freishtat Brennan Harmon Jonathan M. Mansbach Pedro A. Piedra Zhaozhong Zhu Carlos A. Camargo Kohei Hasegawa
author_facet	Yoshihiko Raita Marcos Pérez-Losada Robert J. Freishtat Brennan Harmon Jonathan M. Mansbach Pedro A. Piedra Zhaozhong Zhu Carlos A. Camargo Kohei Hasegawa
author_sort	Yoshihiko Raita
title	Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
title_short	Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
title_full	Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
title_fullStr	Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
title_full_unstemmed	Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
title_sort	integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6c472cd962914c2c8b3f0373e27d5a0a
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Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma

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