Identification of atrial fibrillation associated genes and functional non-coding variants

The majority of disease-associated genetic variants lie in non-coding regions. Here the authors generated and compiled human transcriptomic, epigenomic and chromatin conformation datasets, to identify genes associated with atrial fibrillation and functional non-coding variants.

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Autores principales:	Antoinette F. van Ouwerkerk, Fernanda M. Bosada, Karel van Duijvenboden, Matthew C. Hill, Lindsey E. Montefiori, Koen T. Scholman, Jia Liu, Antoine A. F. de Vries, Bastiaan J. Boukens, Patrick T. Ellinor, Marie José T. H. Goumans, Igor R. Efimov, Marcelo A. Nobrega, Phil Barnett, James F. Martin, Vincent M. Christoffels
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c47420fc1c646169658c86522780b7c
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spelling	oai:doaj.org-article:6c47420fc1c646169658c86522780b7c2021-12-02T16:57:54ZIdentification of atrial fibrillation associated genes and functional non-coding variants10.1038/s41467-019-12721-52041-1723https://doaj.org/article/6c47420fc1c646169658c86522780b7c2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12721-5https://doaj.org/toc/2041-1723The majority of disease-associated genetic variants lie in non-coding regions. Here the authors generated and compiled human transcriptomic, epigenomic and chromatin conformation datasets, to identify genes associated with atrial fibrillation and functional non-coding variants.Antoinette F. van OuwerkerkFernanda M. BosadaKarel van DuijvenbodenMatthew C. HillLindsey E. MontefioriKoen T. ScholmanJia LiuAntoine A. F. de VriesBastiaan J. BoukensPatrick T. EllinorMarie José T. H. GoumansIgor R. EfimovMarcelo A. NobregaPhil BarnettJames F. MartinVincent M. ChristoffelsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Antoinette F. van Ouwerkerk Fernanda M. Bosada Karel van Duijvenboden Matthew C. Hill Lindsey E. Montefiori Koen T. Scholman Jia Liu Antoine A. F. de Vries Bastiaan J. Boukens Patrick T. Ellinor Marie José T. H. Goumans Igor R. Efimov Marcelo A. Nobrega Phil Barnett James F. Martin Vincent M. Christoffels Identification of atrial fibrillation associated genes and functional non-coding variants
description	The majority of disease-associated genetic variants lie in non-coding regions. Here the authors generated and compiled human transcriptomic, epigenomic and chromatin conformation datasets, to identify genes associated with atrial fibrillation and functional non-coding variants.
format	article
author	Antoinette F. van Ouwerkerk Fernanda M. Bosada Karel van Duijvenboden Matthew C. Hill Lindsey E. Montefiori Koen T. Scholman Jia Liu Antoine A. F. de Vries Bastiaan J. Boukens Patrick T. Ellinor Marie José T. H. Goumans Igor R. Efimov Marcelo A. Nobrega Phil Barnett James F. Martin Vincent M. Christoffels
author_facet	Antoinette F. van Ouwerkerk Fernanda M. Bosada Karel van Duijvenboden Matthew C. Hill Lindsey E. Montefiori Koen T. Scholman Jia Liu Antoine A. F. de Vries Bastiaan J. Boukens Patrick T. Ellinor Marie José T. H. Goumans Igor R. Efimov Marcelo A. Nobrega Phil Barnett James F. Martin Vincent M. Christoffels
author_sort	Antoinette F. van Ouwerkerk
title	Identification of atrial fibrillation associated genes and functional non-coding variants
title_short	Identification of atrial fibrillation associated genes and functional non-coding variants
title_full	Identification of atrial fibrillation associated genes and functional non-coding variants
title_fullStr	Identification of atrial fibrillation associated genes and functional non-coding variants
title_full_unstemmed	Identification of atrial fibrillation associated genes and functional non-coding variants
title_sort	identification of atrial fibrillation associated genes and functional non-coding variants
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6c47420fc1c646169658c86522780b7c
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Identification of atrial fibrillation associated genes and functional non-coding variants

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