Mechanochemical Synthesis of A Novel Eutectic of the Antimicrobial Nitazoxanide with Improved Dissolution Performance

Background: Nitazoxanide (NTZ) is a broad spectrum antimicrobial agent with poor aqueous solubility and low bioavailability. Thus, the generation of new solid forms of NTZ is relevant to improve its unfavorable properties. The present study deals with the application of mechanochemistry for the prep...

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Autores principales: Octavio E. Fandiño, Flavia P Bruno, Gustavo A. Monti, Norma R. Sperandeo
Formato: article
Lenguaje:EN
Publicado: Tabriz University of Medical Sciences 2021
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Acceso en línea:https://doaj.org/article/6c47f72ff9d34083b049dc5cd96f36b4
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