Network analyses reveal pervasive functional regulation between proteases in the human protease web.
Proteolytic processing is an irreversible posttranslational modification affecting a large portion of the proteome. Protease-cleaved mediators frequently exhibit altered activity, and biological pathways are often regulated by proteolytic processing. Many of these mechanisms have not been appreciate...
Guardado en:
Autores principales: | Nikolaus Fortelny, Jennifer H Cox, Reinhild Kappelhoff, Amanda E Starr, Philipp F Lange, Paul Pavlidis, Christopher M Overall |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/6c499b3dfca44b46afedb024015fd05d |
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