A dimeric fluorescent protein yields a bright, red-shifted GEVI capable of population signals in brain slice

Abstract A bright, red-shifted Genetically Encoded Voltage Indicator (GEVI) was developed using a modified version of the fluorescent protein, tdTomato. Dimerization of the fluorescent domain for ArcLight-type GEVIs has been shown to affect the signal size of the voltage-dependent optical signal. Fo...

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Autores principales: Bumjun Yi, Bok Eum Kang, Sungmoo Lee, Sophie Braubach, Bradley J. Baker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6c4f6b7bf7454043ad72e21299734f5c
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