Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*

Six dogs each with open and closed-cervix pyometra (Group I and II) were medically managed with mifepristone @ 2.5mg/kg body weight orally twice daily for five days, followed by cloprostenol @ 5µg/kg body weight subcutaneously on every alternate day after ensuring cervical patency, till complete ev...

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Autores principales:	D. Nayana, B. Bibin Becha, C. Jayakumar, M.P. Unnikrishnan, Syam K. Venugopal
Formato:	article
Lenguaje:	EN
Publicado:	Director of Academics and Research, Kerala Veterinary and Animal Sciences University 2021
Materias:	pyometra haemato-biochemistry medical management Animal biochemistry QP501-801 Science (General) Q1-390
Acceso en línea:	https://doaj.org/article/6c6163ce9c0344f9a47eb5486912d71c
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spelling	oai:doaj.org-article:6c6163ce9c0344f9a47eb5486912d71c2021-11-18T14:02:04ZHaemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*10.51966/jvas.2021.52.3.281-2850971-07012582-0605https://doaj.org/article/6c6163ce9c0344f9a47eb5486912d71c2021-07-01T00:00:00Zhttps://www.jvas.in/public_html/upload/article_file/article_file_r0qmg8.pdf?t=r0qmg8https://doaj.org/toc/0971-0701https://doaj.org/toc/2582-0605Six dogs each with open and closed-cervix pyometra (Group I and II) were medically managed with mifepristone @ 2.5mg/kg body weight orally twice daily for five days, followed by cloprostenol @ 5µg/kg body weight subcutaneously on every alternate day after ensuring cervical patency, till complete evacuation of uterus was assessed by ultrasonography. Haematological and serum biochemical values were estimated on the day of presentation. The treatment response was assessed by reviewing both haematological and serum biochemical values further on days 3, 7, 14 and 21 of treatment. The mean total erythrocyte count (TEC), haemoglobin concentration and volume of packed red cells (VPRC) were significantly lower and mean total leucocyte count (TLC) was significantly higher in all animals of both groups during the day of presentation. The values significantly improved after initiation of treatment. Total thrombocyte count, serum total protein, albumin, BUN and serum creatinine levels were within the normal range. TEC, TLC, Hb concentration, VPRC could be used for prognostic markers of treatment evaluation in canine pyometra.D. NayanaB. Bibin BechaC. JayakumarM.P. UnnikrishnanSyam K. VenugopalDirector of Academics and Research, Kerala Veterinary and Animal Sciences Universityarticlepyometrahaemato-biochemistrymedical managementAnimal biochemistryQP501-801Science (General)Q1-390ENJournal of Veterinary and Animal Sciences, Vol 52, Iss 3, Pp 281-285 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	pyometra haemato-biochemistry medical management Animal biochemistry QP501-801 Science (General) Q1-390
spellingShingle	pyometra haemato-biochemistry medical management Animal biochemistry QP501-801 Science (General) Q1-390 D. Nayana B. Bibin Becha C. Jayakumar M.P. Unnikrishnan Syam K. Venugopal Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
description	Six dogs each with open and closed-cervix pyometra (Group I and II) were medically managed with mifepristone @ 2.5mg/kg body weight orally twice daily for five days, followed by cloprostenol @ 5µg/kg body weight subcutaneously on every alternate day after ensuring cervical patency, till complete evacuation of uterus was assessed by ultrasonography. Haematological and serum biochemical values were estimated on the day of presentation. The treatment response was assessed by reviewing both haematological and serum biochemical values further on days 3, 7, 14 and 21 of treatment. The mean total erythrocyte count (TEC), haemoglobin concentration and volume of packed red cells (VPRC) were significantly lower and mean total leucocyte count (TLC) was significantly higher in all animals of both groups during the day of presentation. The values significantly improved after initiation of treatment. Total thrombocyte count, serum total protein, albumin, BUN and serum creatinine levels were within the normal range. TEC, TLC, Hb concentration, VPRC could be used for prognostic markers of treatment evaluation in canine pyometra.
format	article
author	D. Nayana B. Bibin Becha C. Jayakumar M.P. Unnikrishnan Syam K. Venugopal
author_facet	D. Nayana B. Bibin Becha C. Jayakumar M.P. Unnikrishnan Syam K. Venugopal
author_sort	D. Nayana
title	Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
title_short	Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
title_full	Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
title_fullStr	Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
title_full_unstemmed	Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
title_sort	haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*
publisher	Director of Academics and Research, Kerala Veterinary and Animal Sciences University
publishDate	2021
url	https://doaj.org/article/6c6163ce9c0344f9a47eb5486912d71c
work_keys_str_mv	AT dnayana haematobiochemicalstudiesinmedicallymanagedopenandclosedcervixpyometraindogs AT bbibinbecha haematobiochemicalstudiesinmedicallymanagedopenandclosedcervixpyometraindogs AT cjayakumar haematobiochemicalstudiesinmedicallymanagedopenandclosedcervixpyometraindogs AT mpunnikrishnan haematobiochemicalstudiesinmedicallymanagedopenandclosedcervixpyometraindogs AT syamkvenugopal haematobiochemicalstudiesinmedicallymanagedopenandclosedcervixpyometraindogs
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Haemato-biochemical studies in medically managed open and closed-cervix pyometra in dogs*

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