Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton

Stabilizing lipid nanoparticles and lipidprotein assemblies is challenging owing to lipid dynamics and protein instability. Here, the authors report on the reversible encapsulation of liposomes and proteoliposomes in a metalorganic framework permitting months-long room temp storage.

Guardado en:

Detalles Bibliográficos
Autores principales:	Fabian C. Herbert, Sameera S. Abeyrathna, Nisansala S. Abeyrathna, Yalini H. Wijesundara, Olivia R. Brohlin, Francesco Carraro, Heinz Amenitsch, Paolo Falcaro, Michael A. Luzuriaga, Alejandra Durand-Silva, Shashini D. Diwakara, Ronald A. Smaldone, Gabriele Meloni, Jeremiah J. Gassensmith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c63006885b6455ba0e68e5b925e37f0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6c63006885b6455ba0e68e5b925e37f0
record_format	dspace
spelling	oai:doaj.org-article:6c63006885b6455ba0e68e5b925e37f02021-12-02T14:25:17ZStabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton10.1038/s41467-021-22285-y2041-1723https://doaj.org/article/6c63006885b6455ba0e68e5b925e37f02021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22285-yhttps://doaj.org/toc/2041-1723Stabilizing lipid nanoparticles and lipidprotein assemblies is challenging owing to lipid dynamics and protein instability. Here, the authors report on the reversible encapsulation of liposomes and proteoliposomes in a metalorganic framework permitting months-long room temp storage.Fabian C. HerbertSameera S. AbeyrathnaNisansala S. AbeyrathnaYalini H. WijesundaraOlivia R. BrohlinFrancesco CarraroHeinz AmenitschPaolo FalcaroMichael A. LuzuriagaAlejandra Durand-SilvaShashini D. DiwakaraRonald A. SmaldoneGabriele MeloniJeremiah J. GassensmithNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fabian C. Herbert Sameera S. Abeyrathna Nisansala S. Abeyrathna Yalini H. Wijesundara Olivia R. Brohlin Francesco Carraro Heinz Amenitsch Paolo Falcaro Michael A. Luzuriaga Alejandra Durand-Silva Shashini D. Diwakara Ronald A. Smaldone Gabriele Meloni Jeremiah J. Gassensmith Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
description	Stabilizing lipid nanoparticles and lipidprotein assemblies is challenging owing to lipid dynamics and protein instability. Here, the authors report on the reversible encapsulation of liposomes and proteoliposomes in a metalorganic framework permitting months-long room temp storage.
format	article
author	Fabian C. Herbert Sameera S. Abeyrathna Nisansala S. Abeyrathna Yalini H. Wijesundara Olivia R. Brohlin Francesco Carraro Heinz Amenitsch Paolo Falcaro Michael A. Luzuriaga Alejandra Durand-Silva Shashini D. Diwakara Ronald A. Smaldone Gabriele Meloni Jeremiah J. Gassensmith
author_facet	Fabian C. Herbert Sameera S. Abeyrathna Nisansala S. Abeyrathna Yalini H. Wijesundara Olivia R. Brohlin Francesco Carraro Heinz Amenitsch Paolo Falcaro Michael A. Luzuriaga Alejandra Durand-Silva Shashini D. Diwakara Ronald A. Smaldone Gabriele Meloni Jeremiah J. Gassensmith
author_sort	Fabian C. Herbert
title	Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
title_short	Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
title_full	Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
title_fullStr	Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
title_full_unstemmed	Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
title_sort	stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6c63006885b6455ba0e68e5b925e37f0
work_keys_str_mv	AT fabiancherbert stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT sameerasabeyrathna stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT nisansalasabeyrathna stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT yalinihwijesundara stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT oliviarbrohlin stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT francescocarraro stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT heinzamenitsch stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT paolofalcaro stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT michaelaluzuriaga stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT alejandradurandsilva stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT shashiniddiwakara stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT ronaldasmaldone stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT gabrielemeloni stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton AT jeremiahjgassensmith stabilizationofsupramolecularmembraneproteinlipidbilayerassembliesthroughimmobilizationinacrystallineexoskeleton
_version_	1718391373464338432

Stabilization of supramolecular membrane protein–lipid bilayer assemblies through immobilization in a crystalline exoskeleton

Ejemplares similares