An evolutionary path to altered cofactor specificity in a metalloenzyme

Many metalloenzymes are highly specific for their cognate metal ion but the molecular principles underlying this specificity often remain unclear. Here, the authors characterize the structural and biochemical basis for the different metal specificity of two evolutionarily related superoxide dismutas...

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Autores principales: Anna Barwinska-Sendra, Yuritzi M. Garcia, Kacper M. Sendra, Arnaud Baslé, Eilidh S. Mackenzie, Emma Tarrant, Patrick Card, Leandro C. Tabares, Cédric Bicep, Sun Un, Thomas E. Kehl-Fie, Kevin J. Waldron
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6c637b09e75b4404830df194ffd54159
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