Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system
Legionella pneumophila employs the Type 4B secretion system (T4BSS) to translocate more than 300 effector proteins into the host cell during infection. Here the authors present the crystal structure of the DotM soluble domain and give mechanistic insights into the recruitment of Glu-rich motif-conta...
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Nature Portfolio
2018
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oai:doaj.org-article:6c642b7b193d45158274212a718657672021-12-02T15:34:06ZLegionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system10.1038/s41467-017-02578-x2041-1723https://doaj.org/article/6c642b7b193d45158274212a718657672018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02578-xhttps://doaj.org/toc/2041-1723Legionella pneumophila employs the Type 4B secretion system (T4BSS) to translocate more than 300 effector proteins into the host cell during infection. Here the authors present the crystal structure of the DotM soluble domain and give mechanistic insights into the recruitment of Glu-rich motif-containing effectors to the T4BSS.Amit MeirDavid ChetritLuying LiuCraig R. RoyGabriel WaksmanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018) |
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Science Q Amit Meir David Chetrit Luying Liu Craig R. Roy Gabriel Waksman Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
description |
Legionella pneumophila employs the Type 4B secretion system (T4BSS) to translocate more than 300 effector proteins into the host cell during infection. Here the authors present the crystal structure of the DotM soluble domain and give mechanistic insights into the recruitment of Glu-rich motif-containing effectors to the T4BSS. |
format |
article |
author |
Amit Meir David Chetrit Luying Liu Craig R. Roy Gabriel Waksman |
author_facet |
Amit Meir David Chetrit Luying Liu Craig R. Roy Gabriel Waksman |
author_sort |
Amit Meir |
title |
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
title_short |
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
title_full |
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
title_fullStr |
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
title_full_unstemmed |
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system |
title_sort |
legionella dotm structure reveals a role in effector recruiting to the type 4b secretion system |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/6c642b7b193d45158274212a71865767 |
work_keys_str_mv |
AT amitmeir legionelladotmstructurerevealsaroleineffectorrecruitingtothetype4bsecretionsystem AT davidchetrit legionelladotmstructurerevealsaroleineffectorrecruitingtothetype4bsecretionsystem AT luyingliu legionelladotmstructurerevealsaroleineffectorrecruitingtothetype4bsecretionsystem AT craigrroy legionelladotmstructurerevealsaroleineffectorrecruitingtothetype4bsecretionsystem AT gabrielwaksman legionelladotmstructurerevealsaroleineffectorrecruitingtothetype4bsecretionsystem |
_version_ |
1718386904925208576 |