Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

Pathogenic microbes can often attach to surfaces and form biofilms that display increased antibiotic resistance. Here, the authors characterize the biosynthesis of a new class of natural products, the cahuitamycins, that inhibit formation of biofilms by the pathogenic bacterium Acinetobacter baumann...

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Autores principales:	Sung Ryeol Park, Ashootosh Tripathi, Jianfeng Wu, Pamela J. Schultz, Isaiah Yim, Thomas J. McQuade, Fengan Yu, Carl-Johan Arevang, Abraham Y. Mensah, Giselle Tamayo-Castillo, Chuanwu Xi, David H. Sherman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c6688779cdc499e8e46cf39d9845bb8
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spelling	oai:doaj.org-article:6c6688779cdc499e8e46cf39d9845bb82021-12-02T16:50:55ZDiscovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway10.1038/ncomms107102041-1723https://doaj.org/article/6c6688779cdc499e8e46cf39d9845bb82016-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms10710https://doaj.org/toc/2041-1723Pathogenic microbes can often attach to surfaces and form biofilms that display increased antibiotic resistance. Here, the authors characterize the biosynthesis of a new class of natural products, the cahuitamycins, that inhibit formation of biofilms by the pathogenic bacterium Acinetobacter baumannii.Sung Ryeol ParkAshootosh TripathiJianfeng WuPamela J. SchultzIsaiah YimThomas J. McQuadeFengan YuCarl-Johan ArevangAbraham Y. MensahGiselle Tamayo-CastilloChuanwu XiDavid H. ShermanNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sung Ryeol Park Ashootosh Tripathi Jianfeng Wu Pamela J. Schultz Isaiah Yim Thomas J. McQuade Fengan Yu Carl-Johan Arevang Abraham Y. Mensah Giselle Tamayo-Castillo Chuanwu Xi David H. Sherman Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
description	Pathogenic microbes can often attach to surfaces and form biofilms that display increased antibiotic resistance. Here, the authors characterize the biosynthesis of a new class of natural products, the cahuitamycins, that inhibit formation of biofilms by the pathogenic bacterium Acinetobacter baumannii.
format	article
author	Sung Ryeol Park Ashootosh Tripathi Jianfeng Wu Pamela J. Schultz Isaiah Yim Thomas J. McQuade Fengan Yu Carl-Johan Arevang Abraham Y. Mensah Giselle Tamayo-Castillo Chuanwu Xi David H. Sherman
author_facet	Sung Ryeol Park Ashootosh Tripathi Jianfeng Wu Pamela J. Schultz Isaiah Yim Thomas J. McQuade Fengan Yu Carl-Johan Arevang Abraham Y. Mensah Giselle Tamayo-Castillo Chuanwu Xi David H. Sherman
author_sort	Sung Ryeol Park
title	Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
title_short	Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
title_full	Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
title_fullStr	Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
title_full_unstemmed	Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
title_sort	discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/6c6688779cdc499e8e46cf39d9845bb8
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Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway

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