Using multiple Mendelian randomization approaches and genetic correlations to understand obesity, urate, and gout

Abstract Observational studies suggest relationships between obesity, urate, and gout but are possibly confounded. We assessed whether genetically determined obesity, higher urate (and related traits), and gout were causal using multiple Mendelian randomization (MR) approaches and linkage disequilib...

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Bibliographic Details
Main Authors: Charleen D. Adams, Brian B. Boutwell
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/6c6a9e3f7469421abbeac1d41ffdb7b7
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