Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells.
Interactions between antigen-presenting dendritic cells (DCs) and T cells are essential for the induction of an immune response. However, during malaria infection, DC function is compromised and immune responses against parasite and heterologous antigens are reduced. Here, we demonstrate that malari...
Guardado en:
Autores principales: | Owain R Millington, Vivienne B Gibson, Catherine M Rush, Bernd H Zinselmeyer, R Stephen Phillips, Paul Garside, James M Brewer |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2007
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6c6e1c6e87f9459890b2c00832c88a0b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines.
por: Troels R Petersen, et al.
Publicado: (2011) -
HIV/SIV infection primes monocytes and dendritic cells for apoptosis.
por: Mireille Laforge, et al.
Publicado: (2011) -
Interferon priming is essential for human CD34+ cell-derived plasmacytoid dendritic cell maturation and function
por: A. Laustsen, et al.
Publicado: (2018) -
Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity
por: Mubeen M. Mosaheb, et al.
Publicado: (2020) -
Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner
por: Zoran V. Popovic, et al.
Publicado: (2017)