Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses.

Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses.

Neddylation, an important type of post-translational modification, has been implicated in innate and adapted immunity. But the role of neddylation in innate immune response against RNA viruses remains elusive. Here we report that neddylation promotes RNA virus-induced type I IFN production, especial...

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Autores principales: Min Zhao, Yaolin Zhang, Xiqin Yang, Jiayang Jin, Zhuo Shen, Xiaoyao Feng, Tao Zou, Lijiao Deng, Daohai Cheng, Xueting Zhang, Cheng Qin, Chunxiao Niu, Zhenjie Ye, Xueying Zhang, Jia He, Chunmei Hou, Ge Li, Gencheng Han, Qianqian Cheng, Qingyang Wang, Lin Wei, Jie Dong, Jiyan Zhang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/6c71f2746fe440d784de08ef8d781327
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