High-resolution visualization of H3 variants during replication reveals their controlled recycling

Epigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for...

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Autores principales: Camille Clément, Guillermo A. Orsi, Alberto Gatto, Ekaterina Boyarchuk, Audrey Forest, Bassam Hajj, Judith Miné-Hattab, Mickaël Garnier, Zachary A. Gurard-Levin, Jean-Pierre Quivy, Geneviève Almouzni
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6c76f62ba9cb4bb9903ec28038c67081
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spelling oai:doaj.org-article:6c76f62ba9cb4bb9903ec28038c670812021-12-02T15:34:07ZHigh-resolution visualization of H3 variants during replication reveals their controlled recycling10.1038/s41467-018-05697-12041-1723https://doaj.org/article/6c76f62ba9cb4bb9903ec28038c670812018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05697-1https://doaj.org/toc/2041-1723Epigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for the histone chaperone ASF1 in the redistribution of parental histones.Camille ClémentGuillermo A. OrsiAlberto GattoEkaterina BoyarchukAudrey ForestBassam HajjJudith Miné-HattabMickaël GarnierZachary A. Gurard-LevinJean-Pierre QuivyGeneviève AlmouzniNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Camille Clément
Guillermo A. Orsi
Alberto Gatto
Ekaterina Boyarchuk
Audrey Forest
Bassam Hajj
Judith Miné-Hattab
Mickaël Garnier
Zachary A. Gurard-Levin
Jean-Pierre Quivy
Geneviève Almouzni
High-resolution visualization of H3 variants during replication reveals their controlled recycling
description Epigenetic modifications are a key contributor to cell identity, and their propagation is crucial for proper development. Here the authors use a super-resolution microscopy approach to reveal how histone variants are faithfully transmitted during genome duplication, and reveal an important role for the histone chaperone ASF1 in the redistribution of parental histones.
format article
author Camille Clément
Guillermo A. Orsi
Alberto Gatto
Ekaterina Boyarchuk
Audrey Forest
Bassam Hajj
Judith Miné-Hattab
Mickaël Garnier
Zachary A. Gurard-Levin
Jean-Pierre Quivy
Geneviève Almouzni
author_facet Camille Clément
Guillermo A. Orsi
Alberto Gatto
Ekaterina Boyarchuk
Audrey Forest
Bassam Hajj
Judith Miné-Hattab
Mickaël Garnier
Zachary A. Gurard-Levin
Jean-Pierre Quivy
Geneviève Almouzni
author_sort Camille Clément
title High-resolution visualization of H3 variants during replication reveals their controlled recycling
title_short High-resolution visualization of H3 variants during replication reveals their controlled recycling
title_full High-resolution visualization of H3 variants during replication reveals their controlled recycling
title_fullStr High-resolution visualization of H3 variants during replication reveals their controlled recycling
title_full_unstemmed High-resolution visualization of H3 variants during replication reveals their controlled recycling
title_sort high-resolution visualization of h3 variants during replication reveals their controlled recycling
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6c76f62ba9cb4bb9903ec28038c67081
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