Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission

Little information is available on molecular changes in response to treatment of rheumatoid arthritis (RA). Here the authors report a multi-omics study collecting patients' transcriptome, proteome, and immunophenotype data to help understand the impact of drug treatments on RA molecular phenoty...

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Autores principales: Shinya Tasaki, Katsuya Suzuki, Yoshiaki Kassai, Masaru Takeshita, Atsuko Murota, Yasushi Kondo, Tatsuya Ando, Yusuke Nakayama, Yuumi Okuzono, Maiko Takiguchi, Rina Kurisu, Takahiro Miyazaki, Keiko Yoshimoto, Hidekata Yasuoka, Kunihiro Yamaoka, Rimpei Morita, Akihiko Yoshimura, Hiroyoshi Toyoshiba, Tsutomu Takeuchi
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6c7bcbecbfa5477e86bcbca7581072ed
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spelling oai:doaj.org-article:6c7bcbecbfa5477e86bcbca7581072ed2021-12-02T17:31:45ZMulti-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission10.1038/s41467-018-05044-42041-1723https://doaj.org/article/6c7bcbecbfa5477e86bcbca7581072ed2018-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05044-4https://doaj.org/toc/2041-1723Little information is available on molecular changes in response to treatment of rheumatoid arthritis (RA). Here the authors report a multi-omics study collecting patients' transcriptome, proteome, and immunophenotype data to help understand the impact of drug treatments on RA molecular phenotypes.Shinya TasakiKatsuya SuzukiYoshiaki KassaiMasaru TakeshitaAtsuko MurotaYasushi KondoTatsuya AndoYusuke NakayamaYuumi OkuzonoMaiko TakiguchiRina KurisuTakahiro MiyazakiKeiko YoshimotoHidekata YasuokaKunihiro YamaokaRimpei MoritaAkihiko YoshimuraHiroyoshi ToyoshibaTsutomu TakeuchiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Shinya Tasaki
Katsuya Suzuki
Yoshiaki Kassai
Masaru Takeshita
Atsuko Murota
Yasushi Kondo
Tatsuya Ando
Yusuke Nakayama
Yuumi Okuzono
Maiko Takiguchi
Rina Kurisu
Takahiro Miyazaki
Keiko Yoshimoto
Hidekata Yasuoka
Kunihiro Yamaoka
Rimpei Morita
Akihiko Yoshimura
Hiroyoshi Toyoshiba
Tsutomu Takeuchi
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
description Little information is available on molecular changes in response to treatment of rheumatoid arthritis (RA). Here the authors report a multi-omics study collecting patients' transcriptome, proteome, and immunophenotype data to help understand the impact of drug treatments on RA molecular phenotypes.
format article
author Shinya Tasaki
Katsuya Suzuki
Yoshiaki Kassai
Masaru Takeshita
Atsuko Murota
Yasushi Kondo
Tatsuya Ando
Yusuke Nakayama
Yuumi Okuzono
Maiko Takiguchi
Rina Kurisu
Takahiro Miyazaki
Keiko Yoshimoto
Hidekata Yasuoka
Kunihiro Yamaoka
Rimpei Morita
Akihiko Yoshimura
Hiroyoshi Toyoshiba
Tsutomu Takeuchi
author_facet Shinya Tasaki
Katsuya Suzuki
Yoshiaki Kassai
Masaru Takeshita
Atsuko Murota
Yasushi Kondo
Tatsuya Ando
Yusuke Nakayama
Yuumi Okuzono
Maiko Takiguchi
Rina Kurisu
Takahiro Miyazaki
Keiko Yoshimoto
Hidekata Yasuoka
Kunihiro Yamaoka
Rimpei Morita
Akihiko Yoshimura
Hiroyoshi Toyoshiba
Tsutomu Takeuchi
author_sort Shinya Tasaki
title Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
title_short Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
title_full Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
title_fullStr Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
title_full_unstemmed Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
title_sort multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6c7bcbecbfa5477e86bcbca7581072ed
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