Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation

Understanding the biomolecular corona is of key importance to nanomedicine. Here, the authors report on cryo-electron and tomographic imaging of the corona formed on model nanoparticles and the 3D reconstruction of the corona to study the distribution and association of the biomolecules with the nan...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Sara Sheibani, Kaustuv Basu, Ali Farnudi, Aliakbar Ashkarran, Muneyoshi Ichikawa, John F. Presley, Khanh Huy Bui, Mohammad Reza Ejtehadi, Hojatollah Vali, Morteza Mahmoudi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/6c7eeba2116a47d78bbca5f63e0707d3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:6c7eeba2116a47d78bbca5f63e0707d3
record_format dspace
spelling oai:doaj.org-article:6c7eeba2116a47d78bbca5f63e0707d32021-12-02T13:57:54ZNanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation10.1038/s41467-020-20884-92041-1723https://doaj.org/article/6c7eeba2116a47d78bbca5f63e0707d32021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20884-9https://doaj.org/toc/2041-1723Understanding the biomolecular corona is of key importance to nanomedicine. Here, the authors report on cryo-electron and tomographic imaging of the corona formed on model nanoparticles and the 3D reconstruction of the corona to study the distribution and association of the biomolecules with the nanoparticle.Sara SheibaniKaustuv BasuAli FarnudiAliakbar AshkarranMuneyoshi IchikawaJohn F. PresleyKhanh Huy BuiMohammad Reza EjtehadiHojatollah ValiMorteza MahmoudiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Sara Sheibani
Kaustuv Basu
Ali Farnudi
Aliakbar Ashkarran
Muneyoshi Ichikawa
John F. Presley
Khanh Huy Bui
Mohammad Reza Ejtehadi
Hojatollah Vali
Morteza Mahmoudi
Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
description Understanding the biomolecular corona is of key importance to nanomedicine. Here, the authors report on cryo-electron and tomographic imaging of the corona formed on model nanoparticles and the 3D reconstruction of the corona to study the distribution and association of the biomolecules with the nanoparticle.
format article
author Sara Sheibani
Kaustuv Basu
Ali Farnudi
Aliakbar Ashkarran
Muneyoshi Ichikawa
John F. Presley
Khanh Huy Bui
Mohammad Reza Ejtehadi
Hojatollah Vali
Morteza Mahmoudi
author_facet Sara Sheibani
Kaustuv Basu
Ali Farnudi
Aliakbar Ashkarran
Muneyoshi Ichikawa
John F. Presley
Khanh Huy Bui
Mohammad Reza Ejtehadi
Hojatollah Vali
Morteza Mahmoudi
author_sort Sara Sheibani
title Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
title_short Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
title_full Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
title_fullStr Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
title_full_unstemmed Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
title_sort nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6c7eeba2116a47d78bbca5f63e0707d3
work_keys_str_mv AT sarasheibani nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT kaustuvbasu nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT alifarnudi nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT aliakbarashkarran nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT muneyoshiichikawa nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT johnfpresley nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT khanhhuybui nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT mohammadrezaejtehadi nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT hojatollahvali nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
AT mortezamahmoudi nanoscalecharacterizationofthebiomolecularcoronabycryoelectronmicroscopycryoelectrontomographyandimagesimulation
_version_ 1718392265147154432