Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.

Duchenne muscular dystrophy (DMD) is a progressive and fatal disease of muscle wasting caused by loss of the cytoskeletal protein dystrophin. In the heart, DMD results in progressive cardiomyopathy and dilation of the left ventricle through mechanisms that are not fully understood. Previous reports...

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Bibliographic Details
Main Authors: Matthew S Barnabei, Joseph M Metzger
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
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Online Access:https://doaj.org/article/6c821ddad9ba4c85a2088b9d2f066936
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