Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
Unlike human teeth, mouse incisors grow throughout life, based on stem and progenitor cell activity. Here the authors generate single cell RNA-seq comparative maps of continuously-growing mouse incisor, non-growing mouse molar and human teeth, combined with lineage tracing to reveal dental cell comp...
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Nature Portfolio
2020
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oai:doaj.org-article:6c8df9e45ced47ac834d40d04694da4c2021-12-02T18:48:04ZDental cell type atlas reveals stem and differentiated cell types in mouse and human teeth10.1038/s41467-020-18512-72041-1723https://doaj.org/article/6c8df9e45ced47ac834d40d04694da4c2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18512-7https://doaj.org/toc/2041-1723Unlike human teeth, mouse incisors grow throughout life, based on stem and progenitor cell activity. Here the authors generate single cell RNA-seq comparative maps of continuously-growing mouse incisor, non-growing mouse molar and human teeth, combined with lineage tracing to reveal dental cell complexity.Jan KrivanekRuslan A. SoldatovMaria Eleni KastritiTatiana ChontorotzeaAnna Nele HerdinaJulian PetersenBara SzarowskaMarie LandovaVeronika Kovar MatejovaLydie Izakovicova HollaUlrike KuchlerIvana Vidovic ZdrilicAnushree VijaykumarAnamaria BalicPauline MarangoniOphir D. KleinVitor C. M. NevesVal YianniPaul T. SharpeTibor HarkanyBrian D. MetscherMarc BajénoffMina MinaKaj FriedPeter V. KharchenkoIgor AdameykoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-18 (2020) |
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Science Q Jan Krivanek Ruslan A. Soldatov Maria Eleni Kastriti Tatiana Chontorotzea Anna Nele Herdina Julian Petersen Bara Szarowska Marie Landova Veronika Kovar Matejova Lydie Izakovicova Holla Ulrike Kuchler Ivana Vidovic Zdrilic Anushree Vijaykumar Anamaria Balic Pauline Marangoni Ophir D. Klein Vitor C. M. Neves Val Yianni Paul T. Sharpe Tibor Harkany Brian D. Metscher Marc Bajénoff Mina Mina Kaj Fried Peter V. Kharchenko Igor Adameyko Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
description |
Unlike human teeth, mouse incisors grow throughout life, based on stem and progenitor cell activity. Here the authors generate single cell RNA-seq comparative maps of continuously-growing mouse incisor, non-growing mouse molar and human teeth, combined with lineage tracing to reveal dental cell complexity. |
format |
article |
author |
Jan Krivanek Ruslan A. Soldatov Maria Eleni Kastriti Tatiana Chontorotzea Anna Nele Herdina Julian Petersen Bara Szarowska Marie Landova Veronika Kovar Matejova Lydie Izakovicova Holla Ulrike Kuchler Ivana Vidovic Zdrilic Anushree Vijaykumar Anamaria Balic Pauline Marangoni Ophir D. Klein Vitor C. M. Neves Val Yianni Paul T. Sharpe Tibor Harkany Brian D. Metscher Marc Bajénoff Mina Mina Kaj Fried Peter V. Kharchenko Igor Adameyko |
author_facet |
Jan Krivanek Ruslan A. Soldatov Maria Eleni Kastriti Tatiana Chontorotzea Anna Nele Herdina Julian Petersen Bara Szarowska Marie Landova Veronika Kovar Matejova Lydie Izakovicova Holla Ulrike Kuchler Ivana Vidovic Zdrilic Anushree Vijaykumar Anamaria Balic Pauline Marangoni Ophir D. Klein Vitor C. M. Neves Val Yianni Paul T. Sharpe Tibor Harkany Brian D. Metscher Marc Bajénoff Mina Mina Kaj Fried Peter V. Kharchenko Igor Adameyko |
author_sort |
Jan Krivanek |
title |
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
title_short |
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
title_full |
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
title_fullStr |
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
title_full_unstemmed |
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
title_sort |
dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/6c8df9e45ced47ac834d40d04694da4c |
work_keys_str_mv |
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