Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

There has been a drastic increase in detection of lung nodules, many of which are precancers, preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome sequencing to discern the evolutional trajectory from precancers to invasive lung cancers.

Guardado en:

Detalles Bibliográficos
Autores principales:	Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c98a1e227804a168c18ce27f945729f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6c98a1e227804a168c18ce27f945729f
record_format	dspace
spelling	oai:doaj.org-article:6c98a1e227804a168c18ce27f945729f2021-12-02T14:39:20ZMulti-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma10.1038/s41467-019-10877-82041-1723https://doaj.org/article/6c98a1e227804a168c18ce27f945729f2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10877-8https://doaj.org/toc/2041-1723There has been a drastic increase in detection of lung nodules, many of which are precancers, preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome sequencing to discern the evolutional trajectory from precancers to invasive lung cancers.Xin HuJunya FujimotoLisha YingJunya FukuokaKazuto AshizawaWenyong SunAlexandre ReubenChi-Wan ChowNicholas McGranahanRunzhe ChenJinlin HuMyrna C. GodoyKazuhiro TabataKishio KurodaLei ShiJun LiCarmen BehrensEdwin Roger ParraLatasha D. LittleCurtis GumbsXizeng MaoXingzhi SongSamantha TippenRebecca L. ThorntonHumam KadaraPaul ScheetEmily RoartyEdwin Justin OstrinXu WangBrett W. CarterMara B. AntonoffJianhua ZhangAra A. VaporciyanHarvey PassStephen G. SwisherJohn V. HeymachJ. Jack LeeIgnacio I. WistubaWaun Ki HongP. Andrew FutrealDan SuJianjun ZhangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xin Hu Junya Fujimoto Lisha Ying Junya Fukuoka Kazuto Ashizawa Wenyong Sun Alexandre Reuben Chi-Wan Chow Nicholas McGranahan Runzhe Chen Jinlin Hu Myrna C. Godoy Kazuhiro Tabata Kishio Kuroda Lei Shi Jun Li Carmen Behrens Edwin Roger Parra Latasha D. Little Curtis Gumbs Xizeng Mao Xingzhi Song Samantha Tippen Rebecca L. Thornton Humam Kadara Paul Scheet Emily Roarty Edwin Justin Ostrin Xu Wang Brett W. Carter Mara B. Antonoff Jianhua Zhang Ara A. Vaporciyan Harvey Pass Stephen G. Swisher John V. Heymach J. Jack Lee Ignacio I. Wistuba Waun Ki Hong P. Andrew Futreal Dan Su Jianjun Zhang Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
description	There has been a drastic increase in detection of lung nodules, many of which are precancers, preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome sequencing to discern the evolutional trajectory from precancers to invasive lung cancers.
format	article
author	Xin Hu Junya Fujimoto Lisha Ying Junya Fukuoka Kazuto Ashizawa Wenyong Sun Alexandre Reuben Chi-Wan Chow Nicholas McGranahan Runzhe Chen Jinlin Hu Myrna C. Godoy Kazuhiro Tabata Kishio Kuroda Lei Shi Jun Li Carmen Behrens Edwin Roger Parra Latasha D. Little Curtis Gumbs Xizeng Mao Xingzhi Song Samantha Tippen Rebecca L. Thornton Humam Kadara Paul Scheet Emily Roarty Edwin Justin Ostrin Xu Wang Brett W. Carter Mara B. Antonoff Jianhua Zhang Ara A. Vaporciyan Harvey Pass Stephen G. Swisher John V. Heymach J. Jack Lee Ignacio I. Wistuba Waun Ki Hong P. Andrew Futreal Dan Su Jianjun Zhang
author_facet	Xin Hu Junya Fujimoto Lisha Ying Junya Fukuoka Kazuto Ashizawa Wenyong Sun Alexandre Reuben Chi-Wan Chow Nicholas McGranahan Runzhe Chen Jinlin Hu Myrna C. Godoy Kazuhiro Tabata Kishio Kuroda Lei Shi Jun Li Carmen Behrens Edwin Roger Parra Latasha D. Little Curtis Gumbs Xizeng Mao Xingzhi Song Samantha Tippen Rebecca L. Thornton Humam Kadara Paul Scheet Emily Roarty Edwin Justin Ostrin Xu Wang Brett W. Carter Mara B. Antonoff Jianhua Zhang Ara A. Vaporciyan Harvey Pass Stephen G. Swisher John V. Heymach J. Jack Lee Ignacio I. Wistuba Waun Ki Hong P. Andrew Futreal Dan Su Jianjun Zhang
author_sort	Xin Hu
title	Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
title_short	Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
title_full	Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
title_fullStr	Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
title_full_unstemmed	Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
title_sort	multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/6c98a1e227804a168c18ce27f945729f
work_keys_str_mv	AT xinhu multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT junyafujimoto multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT lishaying multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT junyafukuoka multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT kazutoashizawa multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT wenyongsun multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT alexandrereuben multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT chiwanchow multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT nicholasmcgranahan multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT runzhechen multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT jinlinhu multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT myrnacgodoy multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT kazuhirotabata multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT kishiokuroda multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT leishi multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT junli multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT carmenbehrens multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT edwinrogerparra multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT latashadlittle multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT curtisgumbs multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT xizengmao multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT xingzhisong multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT samanthatippen multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT rebeccalthornton multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT humamkadara multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT paulscheet multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT emilyroarty multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT edwinjustinostrin multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT xuwang multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT brettwcarter multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT marabantonoff multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT jianhuazhang multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT araavaporciyan multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT harveypass multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT stephengswisher multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT johnvheymach multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT jjacklee multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT ignacioiwistuba multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT waunkihong multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT pandrewfutreal multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT dansu multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma AT jianjunzhang multiregionexomesequencingrevealsgenomicevolutionfrompreneoplasiatolungadenocarcinoma
_version_	1718390659705995264

Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma

Ejemplares similares