Validation of skeletal muscle cis-regulatory module predictions reveals nucleotide composition bias in functional enhancers.
We performed a genome-wide scan for muscle-specific cis-regulatory modules (CRMs) using three computational prediction programs. Based on the predictions, 339 candidate CRMs were tested in cell culture with NIH3T3 fibroblasts and C2C12 myoblasts for capacity to direct selective reporter gene express...
Guardado en:
Autores principales: | Andrew T Kwon, Alice Yi Chou, David J Arenillas, Wyeth W Wasserman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/6c9a710453c5402face97518a5837cbf |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
CisMiner: genome-wide in-silico cis-regulatory module prediction by fuzzy itemset mining.
por: Carmen Navarro, et al.
Publicado: (2014) -
Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
por: Vasavi Sundaram, et al.
Publicado: (2017) -
In vivo Hox binding specificity revealed by systematic changes to a single cis regulatory module
por: Carlos Sánchez-Higueras, et al.
Publicado: (2019) -
Sarcopenia, Obesity, and Sarcopenic Obesity: Relationship with Skeletal Muscle Phenotypes and Single Nucleotide Polymorphisms
por: Praval Khanal, et al.
Publicado: (2021) -
Cis-regulatory evolution in prokaryotes revealed by interspecific archaeal hybrids
por: Carlo G. Artieri, et al.
Publicado: (2017)