Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population

Introduction: Anxiety disorders occur in approximately one third of people with Parkinson’s disease (PD), and have a major impact on patient and caregiver wellbeing. In order to better understand and diagnose anxiety in PD patients, we investigated the generalizability of the results of a previous f...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sonja Rutten, Erwin E.H. van Wegen, Ires Ghielen, Bridget Schoon, Odile A. van den Heuvel
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Parkinson’s disease Anxiety Factor analysis Replication Neuropsychiatry Symptom interaction Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/6c9cbb189f784c0e97fb522bbf0c81a8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6c9cbb189f784c0e97fb522bbf0c81a8
record_format	dspace
spelling	oai:doaj.org-article:6c9cbb189f784c0e97fb522bbf0c81a82021-11-18T04:51:20ZSymptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population2590-112510.1016/j.prdoa.2021.100117https://doaj.org/article/6c9cbb189f784c0e97fb522bbf0c81a82021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2590112521000293https://doaj.org/toc/2590-1125Introduction: Anxiety disorders occur in approximately one third of people with Parkinson’s disease (PD), and have a major impact on patient and caregiver wellbeing. In order to better understand and diagnose anxiety in PD patients, we investigated the generalizability of the results of a previous factor analysis on anxiety symptoms to a sample of PD patients with neuropsychiatric symptoms. Methods: In this cross-sectional study, anxiety symptoms were measured with the Beck Anxiety Inventory (BAI) in 123 PD patients who were referred for neuropsychiatric diagnostics and treatment. Subscales of anxiety were analyzed through principal component analysis of BAI items. The associations between BAI subscales and symptoms of motor and cognitive function and depression were assessed through regression analyses. Results: Similar to the previous factor analysis, we found one psychological (affective) and four somatic subscales of anxiety in the BAI. The affective subscale was the principal component explaining 35.9% of the variance. The scores on the total BAI and the affective subscale were significantly associated with depressive symptoms. In a post-hoc analysis, the affective subscale had equal power as compared to the total BAI in predicting whether or not participants were diagnosed with an anxiety disorder after psychiatric evaluation. Conclusion: In this study, we replicated our previous findings of one affective and multiple somatic subscales of the BAI. The 7-item affective subscale of the BAI shows potential as a screening tool for non-episodic anxiety in PD. However, in clinical practice, we recommend evaluating anxiety symptoms in the context of other PD symptoms, including motor, autonomic, and other (neuro)psychiatric symptoms.Sonja RuttenErwin E.H. van WegenIres GhielenBridget SchoonOdile A. van den HeuvelElsevierarticleParkinson’s diseaseAnxietyFactor analysisReplicationNeuropsychiatrySymptom interactionNeurology. Diseases of the nervous systemRC346-429ENClinical Parkinsonism & Related Disorders, Vol 5, Iss , Pp 100117- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Parkinson’s disease Anxiety Factor analysis Replication Neuropsychiatry Symptom interaction Neurology. Diseases of the nervous system RC346-429
spellingShingle	Parkinson’s disease Anxiety Factor analysis Replication Neuropsychiatry Symptom interaction Neurology. Diseases of the nervous system RC346-429 Sonja Rutten Erwin E.H. van Wegen Ires Ghielen Bridget Schoon Odile A. van den Heuvel Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
description	Introduction: Anxiety disorders occur in approximately one third of people with Parkinson’s disease (PD), and have a major impact on patient and caregiver wellbeing. In order to better understand and diagnose anxiety in PD patients, we investigated the generalizability of the results of a previous factor analysis on anxiety symptoms to a sample of PD patients with neuropsychiatric symptoms. Methods: In this cross-sectional study, anxiety symptoms were measured with the Beck Anxiety Inventory (BAI) in 123 PD patients who were referred for neuropsychiatric diagnostics and treatment. Subscales of anxiety were analyzed through principal component analysis of BAI items. The associations between BAI subscales and symptoms of motor and cognitive function and depression were assessed through regression analyses. Results: Similar to the previous factor analysis, we found one psychological (affective) and four somatic subscales of anxiety in the BAI. The affective subscale was the principal component explaining 35.9% of the variance. The scores on the total BAI and the affective subscale were significantly associated with depressive symptoms. In a post-hoc analysis, the affective subscale had equal power as compared to the total BAI in predicting whether or not participants were diagnosed with an anxiety disorder after psychiatric evaluation. Conclusion: In this study, we replicated our previous findings of one affective and multiple somatic subscales of the BAI. The 7-item affective subscale of the BAI shows potential as a screening tool for non-episodic anxiety in PD. However, in clinical practice, we recommend evaluating anxiety symptoms in the context of other PD symptoms, including motor, autonomic, and other (neuro)psychiatric symptoms.
format	article
author	Sonja Rutten Erwin E.H. van Wegen Ires Ghielen Bridget Schoon Odile A. van den Heuvel
author_facet	Sonja Rutten Erwin E.H. van Wegen Ires Ghielen Bridget Schoon Odile A. van den Heuvel
author_sort	Sonja Rutten
title	Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
title_short	Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
title_full	Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
title_fullStr	Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
title_full_unstemmed	Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population
title_sort	symptom dimensions of anxiety in parkinson’s disease: replication study in a neuropsychiatric patient population
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/6c9cbb189f784c0e97fb522bbf0c81a8
work_keys_str_mv	AT sonjarutten symptomdimensionsofanxietyinparkinsonsdiseasereplicationstudyinaneuropsychiatricpatientpopulation AT erwinehvanwegen symptomdimensionsofanxietyinparkinsonsdiseasereplicationstudyinaneuropsychiatricpatientpopulation AT iresghielen symptomdimensionsofanxietyinparkinsonsdiseasereplicationstudyinaneuropsychiatricpatientpopulation AT bridgetschoon symptomdimensionsofanxietyinparkinsonsdiseasereplicationstudyinaneuropsychiatricpatientpopulation AT odileavandenheuvel symptomdimensionsofanxietyinparkinsonsdiseasereplicationstudyinaneuropsychiatricpatientpopulation
_version_	1718424980347158528

Symptom dimensions of anxiety in Parkinson’s disease: Replication study in a neuropsychiatric patient population

Ejemplares similares