A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size

Insulin receptor signaling governs central physiological functions related to cell growth and metabolism. Here the authors use protein complex purification and super-resolution microscopy to show that insulin receptor activity requires association with dystrophin glycoprotein complex and plakoglobin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yara Eid Mutlak, Dina Aweida, Alexandra Volodin, Bar Ayalon, Nitsan Dahan, Anna Parnis, Shenhav Cohen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6c9dbe296ba64797a1152b1bf96ac0cf
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6c9dbe296ba64797a1152b1bf96ac0cf
record_format	dspace
spelling	oai:doaj.org-article:6c9dbe296ba64797a1152b1bf96ac0cf2021-12-02T16:49:27ZA signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size10.1038/s41467-020-14895-92041-1723https://doaj.org/article/6c9dbe296ba64797a1152b1bf96ac0cf2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14895-9https://doaj.org/toc/2041-1723Insulin receptor signaling governs central physiological functions related to cell growth and metabolism. Here the authors use protein complex purification and super-resolution microscopy to show that insulin receptor activity requires association with dystrophin glycoprotein complex and plakoglobin.Yara Eid MutlakDina AweidaAlexandra VolodinBar AyalonNitsan DahanAnna ParnisShenhav CohenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yara Eid Mutlak Dina Aweida Alexandra Volodin Bar Ayalon Nitsan Dahan Anna Parnis Shenhav Cohen A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
description	Insulin receptor signaling governs central physiological functions related to cell growth and metabolism. Here the authors use protein complex purification and super-resolution microscopy to show that insulin receptor activity requires association with dystrophin glycoprotein complex and plakoglobin.
format	article
author	Yara Eid Mutlak Dina Aweida Alexandra Volodin Bar Ayalon Nitsan Dahan Anna Parnis Shenhav Cohen
author_facet	Yara Eid Mutlak Dina Aweida Alexandra Volodin Bar Ayalon Nitsan Dahan Anna Parnis Shenhav Cohen
author_sort	Yara Eid Mutlak
title	A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
title_short	A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
title_full	A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
title_fullStr	A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
title_full_unstemmed	A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
title_sort	signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6c9dbe296ba64797a1152b1bf96ac0cf
work_keys_str_mv	AT yaraeidmutlak asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT dinaaweida asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT alexandravolodin asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT barayalon asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT nitsandahan asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT annaparnis asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT shenhavcohen asignalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT yaraeidmutlak signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT dinaaweida signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT alexandravolodin signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT barayalon signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT nitsandahan signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT annaparnis signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize AT shenhavcohen signalinghubofinsulinreceptordystrophinglycoproteincomplexandplakoglobinregulatesmusclesize
_version_	1718383339381981184

A signaling hub of insulin receptor, dystrophin glycoprotein complex and plakoglobin regulates muscle size

Ejemplares similares