Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism

Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism

Abstract Metformin is a first-line drug in the treatment of type-2 diabetes mellitus (T2DM). In addition to its antigluconeogenic and insulin-sensitizing properties, metformin has emerged as a potent inhibitor of the chronic inflammatory response of macrophages. In particular, metformin treatment ha...

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Autores principales: Thomas S. Postler, Vincent Peng, Dev M. Bhatt, Sankar Ghosh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6c9dde354c9449a39ec178a57d0a2807
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