Epigenetic instability may alter cell state transitions and anticancer drug resistance.

Drug resistance is a significant obstacle to successful and durable anti-cancer therapy. Targeted therapy is often effective during early phases of treatment; however, eventually cancer cells adapt and transition to drug-resistant cells states rendering the treatment ineffective. It is proposed that...

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Autores principales: Anshul Saini, James M Gallo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/6c9e006cf9054e7b99c24469fa567e8f
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