Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma

Caroline N Pham,1 Nathan M Radcliffe,1–3 Daniel M Vu2 1New York University, New York, NY, USA; 2Weill Cornell Medical College, New York, NY, USA; 3New York Eye Surgery Center, New York, NY, USA Purpose: To evaluate the safety and efficacy profile of a sutureless procedure for drainage va...

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Autores principales: Pham CN, Radcliffe NM, Vu DM
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Publicado: Dove Medical Press 2018
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spelling oai:doaj.org-article:6ca3a2e93c324177a4ddd729279830f52021-12-02T03:23:48ZSurgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma1177-5483https://doaj.org/article/6ca3a2e93c324177a4ddd729279830f52018-12-01T00:00:00Zhttps://www.dovepress.com/surgical-outcomes-associated-with-a-sutureless-drainage-valve-implanta-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Caroline N Pham,1 Nathan M Radcliffe,1–3 Daniel M Vu2 1New York University, New York, NY, USA; 2Weill Cornell Medical College, New York, NY, USA; 3New York Eye Surgery Center, New York, NY, USA Purpose: To evaluate the safety and efficacy profile of a sutureless procedure for drainage valve implantation with combined cataract removal and/or endoscopic cyclophotocoagulation (ECP).Materials and methods: A retrospective case series study of consecutive surgeries for Ahmed glaucoma valve (AGV; New World Medical) implantation in a 1-year period was analyzed. The surgery was performed using a Tisseel fibrin sealant (Baxter Healthcare Corporation) in place of sutures. Some subsets within the case series also included a cataract extraction with intraocular lens (CEIOL) insertion and/or ECP (Endo Optiks) within the same procedure. Primary outcomes for this study including efficacy (IOP change, reduction in medications) and safety (complications and reoperations) were measured out to 3 years. Comparisons between subsets were made using ANOVA with post hoc Tukey’s pairwise tests.Results: One hundred twenty-two eyes of 99 patients underwent sutureless AGV implantation surgery. Of the 122, 18 had an AGV implantation only, 46 had an AGV + CEIOL, 35 had an AGV + ECP, and 23 had an AGV + CEIOL + ECP. In total, there was a significant decrease in IOP (P<0.0001) and number of glaucoma medications (P≤0.0054) at each postoperative visit. In a one-way ANOVA, there were no significant differences in mean IOP between the different subsets of surgeries (P>0.05); 10.7% and 14.8% of eyes required a reoperation either for a complication or for uncontrolled glaucoma, respectively.Conclusion: Sutureless valve implantation is associated with a significant reduction in IOP percentage and medication use after the procedure with a safety profile comparable with other glaucoma surgeries. Keywords: Ahmed glaucoma valve, glaucoma surgery, tube shunt surgery Pham CNRadcliffe NMVu DMDove Medical PressarticleAhmed glaucoma valveglaucoma surgerytube shunt surgeryOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 2607-2615 (2018)
institution DOAJ
collection DOAJ
language EN
topic Ahmed glaucoma valve
glaucoma surgery
tube shunt surgery
Ophthalmology
RE1-994
spellingShingle Ahmed glaucoma valve
glaucoma surgery
tube shunt surgery
Ophthalmology
RE1-994
Pham CN
Radcliffe NM
Vu DM
Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
description Caroline N Pham,1 Nathan M Radcliffe,1–3 Daniel M Vu2 1New York University, New York, NY, USA; 2Weill Cornell Medical College, New York, NY, USA; 3New York Eye Surgery Center, New York, NY, USA Purpose: To evaluate the safety and efficacy profile of a sutureless procedure for drainage valve implantation with combined cataract removal and/or endoscopic cyclophotocoagulation (ECP).Materials and methods: A retrospective case series study of consecutive surgeries for Ahmed glaucoma valve (AGV; New World Medical) implantation in a 1-year period was analyzed. The surgery was performed using a Tisseel fibrin sealant (Baxter Healthcare Corporation) in place of sutures. Some subsets within the case series also included a cataract extraction with intraocular lens (CEIOL) insertion and/or ECP (Endo Optiks) within the same procedure. Primary outcomes for this study including efficacy (IOP change, reduction in medications) and safety (complications and reoperations) were measured out to 3 years. Comparisons between subsets were made using ANOVA with post hoc Tukey’s pairwise tests.Results: One hundred twenty-two eyes of 99 patients underwent sutureless AGV implantation surgery. Of the 122, 18 had an AGV implantation only, 46 had an AGV + CEIOL, 35 had an AGV + ECP, and 23 had an AGV + CEIOL + ECP. In total, there was a significant decrease in IOP (P<0.0001) and number of glaucoma medications (P≤0.0054) at each postoperative visit. In a one-way ANOVA, there were no significant differences in mean IOP between the different subsets of surgeries (P>0.05); 10.7% and 14.8% of eyes required a reoperation either for a complication or for uncontrolled glaucoma, respectively.Conclusion: Sutureless valve implantation is associated with a significant reduction in IOP percentage and medication use after the procedure with a safety profile comparable with other glaucoma surgeries. Keywords: Ahmed glaucoma valve, glaucoma surgery, tube shunt surgery 
format article
author Pham CN
Radcliffe NM
Vu DM
author_facet Pham CN
Radcliffe NM
Vu DM
author_sort Pham CN
title Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
title_short Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
title_full Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
title_fullStr Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
title_full_unstemmed Surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
title_sort surgical outcomes associated with a sutureless drainage valve implantation procedure in patients with refractory glaucoma
publisher Dove Medical Press
publishDate 2018
url https://doaj.org/article/6ca3a2e93c324177a4ddd729279830f5
work_keys_str_mv AT phamcn surgicaloutcomesassociatedwithasuturelessdrainagevalveimplantationprocedureinpatientswithrefractoryglaucoma
AT radcliffenm surgicaloutcomesassociatedwithasuturelessdrainagevalveimplantationprocedureinpatientswithrefractoryglaucoma
AT vudm surgicaloutcomesassociatedwithasuturelessdrainagevalveimplantationprocedureinpatientswithrefractoryglaucoma
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