Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice

Abstract In this study we demonstrate that 2 month old APPswe/PS1dE9 mice, a transgenic model of Alzheimer’s disease, exhibited intact short-term memory in Pavlovian hippocampal—dependent contextual fear learning task. However, their long-term memory was impaired. Intra-CA1 infusion of isoproterenol...

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Autor principal: Smitha Karunakaran
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6cac17ed878a4b3990bca3368b193ef9
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