Generation, localization and functions of macrophages during the development of testis

The developmental origins and functions of testis macrophages remain incompletely characterized. Here, the authors show, using histology, high-dimensional mass cytometry and cell fate-mapping data, that interstitial and peritubular macrophages originate from distinct precursors and contribute distin...

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Autores principales:	Emmi Lokka, Laura Lintukorpi, Sheyla Cisneros-Montalvo, Juho-Antti Mäkelä, Sofia Tyystjärvi, Venla Ojasalo, Heidi Gerke, Jorma Toppari, Pia Rantakari, Marko Salmi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6cad7d52a5544679871fa1c143ad8235
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spelling	oai:doaj.org-article:6cad7d52a5544679871fa1c143ad82352021-12-02T19:09:20ZGeneration, localization and functions of macrophages during the development of testis10.1038/s41467-020-18206-02041-1723https://doaj.org/article/6cad7d52a5544679871fa1c143ad82352020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18206-0https://doaj.org/toc/2041-1723The developmental origins and functions of testis macrophages remain incompletely characterized. Here, the authors show, using histology, high-dimensional mass cytometry and cell fate-mapping data, that interstitial and peritubular macrophages originate from distinct precursors and contribute distinctly to spermatogenesis.Emmi LokkaLaura LintukorpiSheyla Cisneros-MontalvoJuho-Antti MäkeläSofia TyystjärviVenla OjasaloHeidi GerkeJorma ToppariPia RantakariMarko SalmiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Emmi Lokka Laura Lintukorpi Sheyla Cisneros-Montalvo Juho-Antti Mäkelä Sofia Tyystjärvi Venla Ojasalo Heidi Gerke Jorma Toppari Pia Rantakari Marko Salmi Generation, localization and functions of macrophages during the development of testis
description	The developmental origins and functions of testis macrophages remain incompletely characterized. Here, the authors show, using histology, high-dimensional mass cytometry and cell fate-mapping data, that interstitial and peritubular macrophages originate from distinct precursors and contribute distinctly to spermatogenesis.
format	article
author	Emmi Lokka Laura Lintukorpi Sheyla Cisneros-Montalvo Juho-Antti Mäkelä Sofia Tyystjärvi Venla Ojasalo Heidi Gerke Jorma Toppari Pia Rantakari Marko Salmi
author_facet	Emmi Lokka Laura Lintukorpi Sheyla Cisneros-Montalvo Juho-Antti Mäkelä Sofia Tyystjärvi Venla Ojasalo Heidi Gerke Jorma Toppari Pia Rantakari Marko Salmi
author_sort	Emmi Lokka
title	Generation, localization and functions of macrophages during the development of testis
title_short	Generation, localization and functions of macrophages during the development of testis
title_full	Generation, localization and functions of macrophages during the development of testis
title_fullStr	Generation, localization and functions of macrophages during the development of testis
title_full_unstemmed	Generation, localization and functions of macrophages during the development of testis
title_sort	generation, localization and functions of macrophages during the development of testis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6cad7d52a5544679871fa1c143ad8235
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Generation, localization and functions of macrophages during the development of testis

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