Binding of NAD<sup>+</sup>-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A <italic toggle="yes">Streptococcus</italic>
ABSTRACT The globally dominant, invasive M1T1 strain of group A Streptococcus (GAS) harbors polymorphisms in the promoter region of an operon that contains the genes encoding streptolysin O (SLO) and NAD+-glycohydrolase (NADase), resulting in high-level expression of these toxins. While both toxins...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
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American Society for Microbiology
2017
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| Accès en ligne: | https://doaj.org/article/6cae00a8860a4b2793d1a8c496d7e96c |
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