Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)

Abstract We aimed to know if radon concentration is associated with municipal mortality due to brain cancer in Galicia, Spain. We designed an ecological study taking as study unit Galician municipalities. To be included, municipalities had to have at least three radon measurements. We correlated rad...

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Autores principales:	Alberto Ruano-Ravina, Nuria Aragonés, Karl T. Kelsey, Mónica Pérez-Ríos, María Piñeiro-Lamas, Gonzalo López-Abente, Juan M. Barros-Dios
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6caf23f7c91942afa146a146b36d8a90
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spelling	oai:doaj.org-article:6caf23f7c91942afa146a146b36d8a902021-12-02T12:32:44ZResidential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)10.1038/s41598-017-03938-92045-2322https://doaj.org/article/6caf23f7c91942afa146a146b36d8a902017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03938-9https://doaj.org/toc/2045-2322Abstract We aimed to know if radon concentration is associated with municipal mortality due to brain cancer in Galicia, Spain. We designed an ecological study taking as study unit Galician municipalities. To be included, municipalities had to have at least three radon measurements. We correlated radon concentrations with municipal mortality due to these malignant tumors during the period 1999–2008. We calculated the relative risk of dying of brain cancers for each municipality and correlated this value with municipal radon concentration using Spearman’s Rho. 251 municipalities were included, with close to 3,500 radon measurements and an average of 14 radon measurements at each municipality. We observed a significant correlation between residential radon with brain cancer mortality for males and females and the intensity of the correlation was higher for females. These results were reinforced when the analysis was restricted to municipalities with more than 5 radon measurements: Spearman’s Rho 0.286 (p-value < 0.001) and Spearman’s Rho 0.509 (p-value < 0.001) for males and females, respectively. These results suggest an association between residential radon and brain cancer mortality. More research using more robust epidemiological designs is needed to confirm these findings.Alberto Ruano-RavinaNuria AragonésKarl T. KelseyMónica Pérez-RíosMaría Piñeiro-LamasGonzalo López-AbenteJuan M. Barros-DiosNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alberto Ruano-Ravina Nuria Aragonés Karl T. Kelsey Mónica Pérez-Ríos María Piñeiro-Lamas Gonzalo López-Abente Juan M. Barros-Dios Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
description	Abstract We aimed to know if radon concentration is associated with municipal mortality due to brain cancer in Galicia, Spain. We designed an ecological study taking as study unit Galician municipalities. To be included, municipalities had to have at least three radon measurements. We correlated radon concentrations with municipal mortality due to these malignant tumors during the period 1999–2008. We calculated the relative risk of dying of brain cancers for each municipality and correlated this value with municipal radon concentration using Spearman’s Rho. 251 municipalities were included, with close to 3,500 radon measurements and an average of 14 radon measurements at each municipality. We observed a significant correlation between residential radon with brain cancer mortality for males and females and the intensity of the correlation was higher for females. These results were reinforced when the analysis was restricted to municipalities with more than 5 radon measurements: Spearman’s Rho 0.286 (p-value < 0.001) and Spearman’s Rho 0.509 (p-value < 0.001) for males and females, respectively. These results suggest an association between residential radon and brain cancer mortality. More research using more robust epidemiological designs is needed to confirm these findings.
format	article
author	Alberto Ruano-Ravina Nuria Aragonés Karl T. Kelsey Mónica Pérez-Ríos María Piñeiro-Lamas Gonzalo López-Abente Juan M. Barros-Dios
author_facet	Alberto Ruano-Ravina Nuria Aragonés Karl T. Kelsey Mónica Pérez-Ríos María Piñeiro-Lamas Gonzalo López-Abente Juan M. Barros-Dios
author_sort	Alberto Ruano-Ravina
title	Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
title_short	Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
title_full	Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
title_fullStr	Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
title_full_unstemmed	Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)
title_sort	residential radon exposure and brain cancer: an ecological study in a radon prone area (galicia, spain)
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/6caf23f7c91942afa146a146b36d8a90
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Residential radon exposure and brain cancer: an ecological study in a radon prone area (Galicia, Spain)

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