Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation

Astrocytic atrophy as a pathological feature of Parkinson’s disease with LRRK2 mutation

Abstract The principal hallmark of Parkinson’s disease (PD) is the selective neurodegeneration of dopaminergic neurones. Mounting evidence suggests that astrocytes may contribute to dopaminergic neurodegeneration through decreased homoeostatic support and deficient neuroprotection. In this study, we...

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Autores principales: Paula Ramos-Gonzalez, Susana Mato, Juan Carlos Chara, Alexei Verkhratsky, Carlos Matute, Fabio Cavaliere
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Neurology. Diseases of the nervous system
RC346-429
Acceso en línea:https://doaj.org/article/6caf315b9ef544218a6118c4473e1b8b
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