PCGF5 is required for neural differentiation of embryonic stem cells

Polycomb-group proteins are key regulators of transcriptional programs that maintain cell identity. Here the authors provide evidence that PCGF5, a subunit of Polycomb Repressor Complex 1, is important for the differentiation of mouse embryonic stem cells towards a neural cell fate.

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Autores principales: Mingze Yao, Xueke Zhou, Jiajian Zhou, Shixin Gong, Gongcheng Hu, Jiao Li, Kaimeng Huang, Ping Lai, Guang Shi, Andrew P. Hutchins, Hao Sun, Huating Wang, Hongjie Yao
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/6cb39efe37fb4508942343a70751b98b
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spelling oai:doaj.org-article:6cb39efe37fb4508942343a70751b98b2021-12-02T14:38:49ZPCGF5 is required for neural differentiation of embryonic stem cells10.1038/s41467-018-03781-02041-1723https://doaj.org/article/6cb39efe37fb4508942343a70751b98b2018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03781-0https://doaj.org/toc/2041-1723Polycomb-group proteins are key regulators of transcriptional programs that maintain cell identity. Here the authors provide evidence that PCGF5, a subunit of Polycomb Repressor Complex 1, is important for the differentiation of mouse embryonic stem cells towards a neural cell fate.Mingze YaoXueke ZhouJiajian ZhouShixin GongGongcheng HuJiao LiKaimeng HuangPing LaiGuang ShiAndrew P. HutchinsHao SunHuating WangHongjie YaoNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mingze Yao
Xueke Zhou
Jiajian Zhou
Shixin Gong
Gongcheng Hu
Jiao Li
Kaimeng Huang
Ping Lai
Guang Shi
Andrew P. Hutchins
Hao Sun
Huating Wang
Hongjie Yao
PCGF5 is required for neural differentiation of embryonic stem cells
description Polycomb-group proteins are key regulators of transcriptional programs that maintain cell identity. Here the authors provide evidence that PCGF5, a subunit of Polycomb Repressor Complex 1, is important for the differentiation of mouse embryonic stem cells towards a neural cell fate.
format article
author Mingze Yao
Xueke Zhou
Jiajian Zhou
Shixin Gong
Gongcheng Hu
Jiao Li
Kaimeng Huang
Ping Lai
Guang Shi
Andrew P. Hutchins
Hao Sun
Huating Wang
Hongjie Yao
author_facet Mingze Yao
Xueke Zhou
Jiajian Zhou
Shixin Gong
Gongcheng Hu
Jiao Li
Kaimeng Huang
Ping Lai
Guang Shi
Andrew P. Hutchins
Hao Sun
Huating Wang
Hongjie Yao
author_sort Mingze Yao
title PCGF5 is required for neural differentiation of embryonic stem cells
title_short PCGF5 is required for neural differentiation of embryonic stem cells
title_full PCGF5 is required for neural differentiation of embryonic stem cells
title_fullStr PCGF5 is required for neural differentiation of embryonic stem cells
title_full_unstemmed PCGF5 is required for neural differentiation of embryonic stem cells
title_sort pcgf5 is required for neural differentiation of embryonic stem cells
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/6cb39efe37fb4508942343a70751b98b
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AT shixingong pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT gongchenghu pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT jiaoli pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT kaimenghuang pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT pinglai pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT guangshi pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT andrewphutchins pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT haosun pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT huatingwang pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
AT hongjieyao pcgf5isrequiredforneuraldifferentiationofembryonicstemcells
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