Critical roles of p53 in epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells.

Critical roles of p53 in epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma cells.

Hepatocellular carcinoma (HCC) is one of the most malignant tumors and the biggest obstacle in curing HCC is its high metastasis potential. Alteration of p53 is the most frequent genetic change found in HCC. Although the biological function of p53 in tumor initiation and progression has been well ch...

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Autores principales: Zheng Wang, Yuhui Jiang, Dongxian Guan, Jingjing Li, Hongkun Yin, Yi Pan, Dong Xie, Yan Chen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/6cbb550d2cc149ab8387282859b18b4a
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