The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

Export of proteins by type three secretion systems occurs through an export gate that is localized in the periplasm. Here, the authors present the cryo-EM structure of the Vibrio mimicus export gate complex with FlhB, which plays a major role in switching of the specificity of secretion substrates a...

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Auteurs principaux: Lucas Kuhlen, Steven Johnson, Andreas Zeitler, Sandra Bäurle, Justin C. Deme, Joseph J.  E. Caesar, Rebecca Debo, Joseph Fisher, Samuel Wagner, Susan M. Lea
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/6cc514e45205439e8975bcd521c5273c
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