Capturing the perfect pose

Capturing the perfect pose

Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leuk...

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Autor principal: Anam Akhtar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/6cc5de40253e45a0ae93910dcaefed33
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spelling oai:doaj.org-article:6cc5de40253e45a0ae93910dcaefed332021-12-02T14:58:44ZCapturing the perfect pose10.1038/s42003-021-02591-32399-3642https://doaj.org/article/6cc5de40253e45a0ae93910dcaefed332021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02591-3https://doaj.org/toc/2399-3642Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis.Anam AkhtarNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-2 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Anam Akhtar
Capturing the perfect pose
description Lipid nanoparticles can be used to deliver nucleic acids for gene expression modulation—but getting them to target specific tissues is an ongoing challenge. In a new study by Dammes et al., a conformation-sensitive targeting strategy is used to achieve better selectivity in silencing gut-homing leukocytes in mouse models of colitis.
format article
author Anam Akhtar
author_facet Anam Akhtar
author_sort Anam Akhtar
title Capturing the perfect pose
title_short Capturing the perfect pose
title_full Capturing the perfect pose
title_fullStr Capturing the perfect pose
title_full_unstemmed Capturing the perfect pose
title_sort capturing the perfect pose
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6cc5de40253e45a0ae93910dcaefed33
work_keys_str_mv AT anamakhtar capturingtheperfectpose
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