Diabetic retinopathy: a tool for cardiovascular risk stratification

Randomized, cross-sectional, and prospective studies have demonstrated that microvascular complications in patients with diabetes are not only the cause of blindness, renal failure and non-traumatic amputations, but also powerful predictors of cardiovascular complications. The pathophysiology of dia...

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Autores principales:	Angelo Avogaro, Gian Paolo Fadini
Formato:	article
Lenguaje:	EN RU
Publicado:	Endocrinology Research Centre 2019
Materias:	diabetes mellitus diabetic retinopathy coronary heart disease heart failure Nutritional diseases. Deficiency diseases RC620-627
Acceso en línea:	https://doaj.org/article/6cd8ef9625e74eceb9609c51fa1ccf17
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spelling	oai:doaj.org-article:6cd8ef9625e74eceb9609c51fa1ccf172021-11-14T09:00:22ZDiabetic retinopathy: a tool for cardiovascular risk stratification2072-03512072-037810.14341/DM10372https://doaj.org/article/6cd8ef9625e74eceb9609c51fa1ccf172019-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/10372https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Randomized, cross-sectional, and prospective studies have demonstrated that microvascular complications in patients with diabetes are not only the cause of blindness, renal failure and non-traumatic amputations, but also powerful predictors of cardiovascular complications. The pathophysiology of diabetic microvascular complications is determined by several factors including epigenetic modifications, and reduced release of circulating progenitor cells by the bone marrow. Identifying microvascular complications, in particular retinopathy, increases the ability to stratify patients in terms of cardiovascular risk. There may no longer be a rational to consider microangiopathy and macroangiopathy as entirely separate entities, but they should most likely be viewed as a continuum of the widespread vascular damage determined by diabetes mellitus.Angelo AvogaroGian Paolo FadiniEndocrinology Research Centrearticlediabetes mellitusdiabetic retinopathycoronary heart diseaseheart failureNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 22, Iss 5, Pp 455-460 (2019)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	diabetes mellitus diabetic retinopathy coronary heart disease heart failure Nutritional diseases. Deficiency diseases RC620-627
spellingShingle	diabetes mellitus diabetic retinopathy coronary heart disease heart failure Nutritional diseases. Deficiency diseases RC620-627 Angelo Avogaro Gian Paolo Fadini Diabetic retinopathy: a tool for cardiovascular risk stratification
description	Randomized, cross-sectional, and prospective studies have demonstrated that microvascular complications in patients with diabetes are not only the cause of blindness, renal failure and non-traumatic amputations, but also powerful predictors of cardiovascular complications. The pathophysiology of diabetic microvascular complications is determined by several factors including epigenetic modifications, and reduced release of circulating progenitor cells by the bone marrow. Identifying microvascular complications, in particular retinopathy, increases the ability to stratify patients in terms of cardiovascular risk. There may no longer be a rational to consider microangiopathy and macroangiopathy as entirely separate entities, but they should most likely be viewed as a continuum of the widespread vascular damage determined by diabetes mellitus.
format	article
author	Angelo Avogaro Gian Paolo Fadini
author_facet	Angelo Avogaro Gian Paolo Fadini
author_sort	Angelo Avogaro
title	Diabetic retinopathy: a tool for cardiovascular risk stratification
title_short	Diabetic retinopathy: a tool for cardiovascular risk stratification
title_full	Diabetic retinopathy: a tool for cardiovascular risk stratification
title_fullStr	Diabetic retinopathy: a tool for cardiovascular risk stratification
title_full_unstemmed	Diabetic retinopathy: a tool for cardiovascular risk stratification
title_sort	diabetic retinopathy: a tool for cardiovascular risk stratification
publisher	Endocrinology Research Centre
publishDate	2019
url	https://doaj.org/article/6cd8ef9625e74eceb9609c51fa1ccf17
work_keys_str_mv	AT angeloavogaro diabeticretinopathyatoolforcardiovascularriskstratification AT gianpaolofadini diabeticretinopathyatoolforcardiovascularriskstratification
_version_	1718429536205406208

Diabetic retinopathy: a tool for cardiovascular risk stratification

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