mSphere of Influence: Start with an Interesting Biological Phenomenon

ABSTRACT Teresa O'Meara works in the field of functional genomics of Candida albicans, with a focus on host-pathogen interactions. In this mSphere of Influence article, she reflects on how papers entitled "Systematic Screens of a Candida albicans Homozygous Deletion Library Decouple Morpho...

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Autor principal:	Teresa O’Meara
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2019
Materias:	Candida albicans Saccharomyces cerevisiae functional genomics Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/6ce571d326634980b9bb964280962c04
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spelling	oai:doaj.org-article:6ce571d326634980b9bb964280962c042021-11-15T15:22:21ZmSphere of Influence: Start with an Interesting Biological Phenomenon10.1128/mSphere.00299-192379-5042https://doaj.org/article/6ce571d326634980b9bb964280962c042019-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSphere.00299-19https://doaj.org/toc/2379-5042ABSTRACT Teresa O'Meara works in the field of functional genomics of Candida albicans, with a focus on host-pathogen interactions. In this mSphere of Influence article, she reflects on how papers entitled "Systematic Screens of a Candida albicans Homozygous Deletion Library Decouple Morphogenetic Switching and Pathogenicity" by S. M. Noble, S. French, L. A. Kohn, V. Chen, and A. D. Johnson (Nat Genet 42:590–598, 2010, https://doi.org/10.1038/ng.605) and "Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci" by E. B. Styles et al. (Cell Syst 3:264–277.e10, 2016, https://doi.org/10.1016/j.cels.2016.08.008) impacted her research and thinking through pioneering functional genomic screens. These articles show the power of combining defined mutant libraries with screens for interesting phenotypes to understand new biology.Teresa O’MearaAmerican Society for MicrobiologyarticleCandida albicansSaccharomyces cerevisiaefunctional genomicsMicrobiologyQR1-502ENmSphere, Vol 4, Iss 3 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Candida albicans Saccharomyces cerevisiae functional genomics Microbiology QR1-502
spellingShingle	Candida albicans Saccharomyces cerevisiae functional genomics Microbiology QR1-502 Teresa O’Meara mSphere of Influence: Start with an Interesting Biological Phenomenon
description	ABSTRACT Teresa O'Meara works in the field of functional genomics of Candida albicans, with a focus on host-pathogen interactions. In this mSphere of Influence article, she reflects on how papers entitled "Systematic Screens of a Candida albicans Homozygous Deletion Library Decouple Morphogenetic Switching and Pathogenicity" by S. M. Noble, S. French, L. A. Kohn, V. Chen, and A. D. Johnson (Nat Genet 42:590–598, 2010, https://doi.org/10.1038/ng.605) and "Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci" by E. B. Styles et al. (Cell Syst 3:264–277.e10, 2016, https://doi.org/10.1016/j.cels.2016.08.008) impacted her research and thinking through pioneering functional genomic screens. These articles show the power of combining defined mutant libraries with screens for interesting phenotypes to understand new biology.
format	article
author	Teresa O’Meara
author_facet	Teresa O’Meara
author_sort	Teresa O’Meara
title	mSphere of Influence: Start with an Interesting Biological Phenomenon
title_short	mSphere of Influence: Start with an Interesting Biological Phenomenon
title_full	mSphere of Influence: Start with an Interesting Biological Phenomenon
title_fullStr	mSphere of Influence: Start with an Interesting Biological Phenomenon
title_full_unstemmed	mSphere of Influence: Start with an Interesting Biological Phenomenon
title_sort	msphere of influence: start with an interesting biological phenomenon
publisher	American Society for Microbiology
publishDate	2019
url	https://doaj.org/article/6ce571d326634980b9bb964280962c04
work_keys_str_mv	AT teresaomeara msphereofinfluencestartwithaninterestingbiologicalphenomenon
_version_	1718428013156106240

mSphere of Influence: Start with an Interesting Biological Phenomenon

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