Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor

Agonist dependency of the second phase access of β-arrestin 2 to the heteromeric µ-V1b receptor

Abstract During the development of analgesic tolerance to morphine, the V1b vasopressin receptor has been proposed to bind to β-arrestin 2 and the µ-opioid receptor to enable their interaction. However, direct evidence of such a high-order complex is lacking. Using bioluminescent resonance energy tr...

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Autores principales: Nuttawadee Ngamlertwong, Hiroyoshi Tsuchiya, Yuta Mochimaru, Morio Azuma, Takahiro Kuchimaru, Taka-aki Koshimizu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/6ce8f72b459e4c499d3b2445fcce5bfd
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