Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry

Masoud Mozafari,1,2 Erfan Salahinejad,1,3 Vahid Shabafrooz,1 Mostafa Yazdimamaghani,1 Daryoosh Vashaee,4 Lobat Tayebi1,5 1Helmerich Advanced Technology Research Center, School of Materials Science and Engineering, Oklahoma State University, Tulsa, OK, USA; 2Biomaterials Group, Faculty of Biomedical...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mozafari M, Salahinejad E, Shabafrooz V, Yazdimamaghani M, Vashaee D, Tayebi L
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/6ceffdfcb3cd4402ad36ee3950b4a5c9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6ceffdfcb3cd4402ad36ee3950b4a5c9
record_format	dspace
spelling	oai:doaj.org-article:6ceffdfcb3cd4402ad36ee3950b4a5c92021-12-02T07:52:11ZMultilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry1176-91141178-2013https://doaj.org/article/6ceffdfcb3cd4402ad36ee3950b4a5c92013-04-01T00:00:00Zhttp://www.dovepress.com/multilayer-bioactive-glasszirconium-titanate-thin-films-in-bone-tissue-a12888https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Masoud Mozafari,1,2 Erfan Salahinejad,1,3 Vahid Shabafrooz,1 Mostafa Yazdimamaghani,1 Daryoosh Vashaee,4 Lobat Tayebi1,5 1Helmerich Advanced Technology Research Center, School of Materials Science and Engineering, Oklahoma State University, Tulsa, OK, USA; 2Biomaterials Group, Faculty of Biomedical Engineering (Center of Excellence), Amirkabir University of Technology, Tehran, Iran; 3Department of Materials Science and Engineering, School of Engineering, Shiraz University, Shiraz, Iran; 4Helmerich Advanced Technology Research Center, School of Electrical and Computer Engineering, Oklahoma State University, Tulsa, OK, USA; 5School of Chemical Engineering, Oklahoma State University, Tulsa, OK, USA Abstract: Surface modification, particularly coatings deposition, is beneficial to tissue-engineering applications. In this work, bioactive glass/zirconium titanate composite thin films were prepared by a sol-gel spin-coating method. The surface features of the coatings were studied by scanning electron microscopy, atomic force microscopy, and spectroscopic reflection analyses. The results show that uniform and sound multilayer thin films were successfully prepared through the optimization of the process variables and the application of carboxymethyl cellulose as a dispersing agent. Also, it was found that the thickness and roughness of the multilayer coatings increase nonlinearly with increasing the number of the layers. This new class of nanocomposite coatings, comprising the bioactive and inert components, is expected not only to enhance bioactivity and biocompatibility, but also to protect the surface of metallic implants against wear and corrosion. Keywords: bioactive glass, zirconium titanate, spin-coating, microstructural properties, bone/dental applications, tissue engineeringMozafari MSalahinejad EShabafrooz VYazdimamaghani MVashaee DTayebi LDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 1665-1672 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Mozafari M Salahinejad E Shabafrooz V Yazdimamaghani M Vashaee D Tayebi L Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
description	Masoud Mozafari,1,2 Erfan Salahinejad,1,3 Vahid Shabafrooz,1 Mostafa Yazdimamaghani,1 Daryoosh Vashaee,4 Lobat Tayebi1,5 1Helmerich Advanced Technology Research Center, School of Materials Science and Engineering, Oklahoma State University, Tulsa, OK, USA; 2Biomaterials Group, Faculty of Biomedical Engineering (Center of Excellence), Amirkabir University of Technology, Tehran, Iran; 3Department of Materials Science and Engineering, School of Engineering, Shiraz University, Shiraz, Iran; 4Helmerich Advanced Technology Research Center, School of Electrical and Computer Engineering, Oklahoma State University, Tulsa, OK, USA; 5School of Chemical Engineering, Oklahoma State University, Tulsa, OK, USA Abstract: Surface modification, particularly coatings deposition, is beneficial to tissue-engineering applications. In this work, bioactive glass/zirconium titanate composite thin films were prepared by a sol-gel spin-coating method. The surface features of the coatings were studied by scanning electron microscopy, atomic force microscopy, and spectroscopic reflection analyses. The results show that uniform and sound multilayer thin films were successfully prepared through the optimization of the process variables and the application of carboxymethyl cellulose as a dispersing agent. Also, it was found that the thickness and roughness of the multilayer coatings increase nonlinearly with increasing the number of the layers. This new class of nanocomposite coatings, comprising the bioactive and inert components, is expected not only to enhance bioactivity and biocompatibility, but also to protect the surface of metallic implants against wear and corrosion. Keywords: bioactive glass, zirconium titanate, spin-coating, microstructural properties, bone/dental applications, tissue engineering
format	article
author	Mozafari M Salahinejad E Shabafrooz V Yazdimamaghani M Vashaee D Tayebi L
author_facet	Mozafari M Salahinejad E Shabafrooz V Yazdimamaghani M Vashaee D Tayebi L
author_sort	Mozafari M
title	Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
title_short	Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
title_full	Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
title_fullStr	Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
title_full_unstemmed	Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
title_sort	multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/6ceffdfcb3cd4402ad36ee3950b4a5c9
work_keys_str_mv	AT mozafarim multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry AT salahinejade multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry AT shabafroozv multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry AT yazdimamaghanim multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry AT vashaeed multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry AT tayebil multilayerbioactiveglasszirconiumtitanatethinfilmsinbonetissueengineeringandregenerativedentistry
_version_	1718399161659817984

Multilayer bioactive glass/zirconium titanate thin films in bone tissue engineering and regenerative dentistry

Ejemplares similares