REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES

When performing ultrasonography of thymus in young children, we have revealed a specific phenomenon, i.e., a significant increase of thymus size in the children of 4 to 6 months old, having been observed at the terms of vaccination with a combined dyphteria/pertussis/tetanus (DPT) vaccine. After exa...

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Autor principal:	O. B. Sirotina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	thymus children vaccination ultrasonography Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/6d00b9af2d8b401e91b36dde79bfb547
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spelling	oai:doaj.org-article:6d00b9af2d8b401e91b36dde79bfb5472021-11-18T08:03:37ZREACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES1563-06252313-741X10.15789/1563-0625-2010-1-2-125-128https://doaj.org/article/6d00b9af2d8b401e91b36dde79bfb5472014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/53https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XWhen performing ultrasonography of thymus in young children, we have revealed a specific phenomenon, i.e., a significant increase of thymus size in the children of 4 to 6 months old, having been observed at the terms of vaccination with a combined dyphteria/pertussis/tetanus (DPT) vaccine. After examining the dimensions, volume, mass and features of thymic blood flow, we have found that, during the DTP vaccinations, 88.7% of the children exhibit an increase in thymic dimensions, along with higher blood flow rates, as compared with the same indices in unvaccinated children. In 11.3% per cent of the cases, the vascularization of thymus was not altered at all, or did not show any changes. To our mind, these ultrasonic parameters of thymic status represent a regular reaction of a key immune organ to a challenge with bacterial antigens, i.e., being an indicator of the primary immune response to DTP vaccination.O. B. SirotinaSPb RAACIarticlethymuschildrenvaccinationultrasonographyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 125-128 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	thymus children vaccination ultrasonography Immunologic diseases. Allergy RC581-607
spellingShingle	thymus children vaccination ultrasonography Immunologic diseases. Allergy RC581-607 O. B. Sirotina REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
description	When performing ultrasonography of thymus in young children, we have revealed a specific phenomenon, i.e., a significant increase of thymus size in the children of 4 to 6 months old, having been observed at the terms of vaccination with a combined dyphteria/pertussis/tetanus (DPT) vaccine. After examining the dimensions, volume, mass and features of thymic blood flow, we have found that, during the DTP vaccinations, 88.7% of the children exhibit an increase in thymic dimensions, along with higher blood flow rates, as compared with the same indices in unvaccinated children. In 11.3% per cent of the cases, the vascularization of thymus was not altered at all, or did not show any changes. To our mind, these ultrasonic parameters of thymic status represent a regular reaction of a key immune organ to a challenge with bacterial antigens, i.e., being an indicator of the primary immune response to DTP vaccination.
format	article
author	O. B. Sirotina
author_facet	O. B. Sirotina
author_sort	O. B. Sirotina
title	REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
title_short	REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
title_full	REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
title_fullStr	REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
title_full_unstemmed	REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES
title_sort	reaction of thymus tu dpt vaccination in children as assessed by ultrasonographic studies
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/6d00b9af2d8b401e91b36dde79bfb547
work_keys_str_mv	AT obsirotina reactionofthymustudptvaccinationinchildrenasassessedbyultrasonographicstudies
_version_	1718422549912616960

REACTION OF THYMUS TU DPT VACCINATION IN CHILDREN AS ASSESSED BY ULTRASONOGRAPHIC STUDIES

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