Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue

Sustained spindle tension applied to sister centromeres during mitosis leads to loss of sister chromatid cohesion which is known as cohesion fatigue. Here the authors show that Aurora A-dependent phosphorylation of CENP-A at the inner centromeres protects bioriented chromosomes against cohesion fati...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Grégory Eot-Houllier, Laura Magnaghi-Jaulin, Géraldine Fulcrand, François-Xavier Moyroud, Solange Monier, Christian Jaulin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6d07d277ba1c4ebfb8d75c5c0d4bd620
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:6d07d277ba1c4ebfb8d75c5c0d4bd620
record_format	dspace
spelling	oai:doaj.org-article:6d07d277ba1c4ebfb8d75c5c0d4bd6202021-12-02T15:33:59ZAurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue10.1038/s41467-018-04089-92041-1723https://doaj.org/article/6d07d277ba1c4ebfb8d75c5c0d4bd6202018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04089-9https://doaj.org/toc/2041-1723Sustained spindle tension applied to sister centromeres during mitosis leads to loss of sister chromatid cohesion which is known as cohesion fatigue. Here the authors show that Aurora A-dependent phosphorylation of CENP-A at the inner centromeres protects bioriented chromosomes against cohesion fatigue.Grégory Eot-HoullierLaura Magnaghi-JaulinGéraldine FulcrandFrançois-Xavier MoyroudSolange MonierChristian JaulinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Grégory Eot-Houllier Laura Magnaghi-Jaulin Géraldine Fulcrand François-Xavier Moyroud Solange Monier Christian Jaulin Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
description	Sustained spindle tension applied to sister centromeres during mitosis leads to loss of sister chromatid cohesion which is known as cohesion fatigue. Here the authors show that Aurora A-dependent phosphorylation of CENP-A at the inner centromeres protects bioriented chromosomes against cohesion fatigue.
format	article
author	Grégory Eot-Houllier Laura Magnaghi-Jaulin Géraldine Fulcrand François-Xavier Moyroud Solange Monier Christian Jaulin
author_facet	Grégory Eot-Houllier Laura Magnaghi-Jaulin Géraldine Fulcrand François-Xavier Moyroud Solange Monier Christian Jaulin
author_sort	Grégory Eot-Houllier
title	Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
title_short	Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
title_full	Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
title_fullStr	Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
title_full_unstemmed	Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
title_sort	aurora a-dependent cenp-a phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6d07d277ba1c4ebfb8d75c5c0d4bd620
work_keys_str_mv	AT gregoryeothoullier auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue AT lauramagnaghijaulin auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue AT geraldinefulcrand auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue AT francoisxaviermoyroud auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue AT solangemonier auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue AT christianjaulin auroraadependentcenpaphosphorylationatinnercentromeresprotectsbiorientedchromosomesagainstcohesionfatigue
_version_	1718386967839768576

Aurora A-dependent CENP-A phosphorylation at inner centromeres protects bioriented chromosomes against cohesion fatigue

Ejemplares similares